Recombinant multi-species M4K4/ MAP4K4/ FLH21957 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAP4K4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: MAP4K4, gene name: MAP4K4, also named as FLH21957, HEL-S-31, HGK, MEKKK4, NIK. The protein encoded by this gene is a member of the serine/threonine protein kinase family. This kinase has been shown to specifically activate MAPK8/JNK. The activation of MAPK8 by this kinase is found to be inhibited by the dominant-negative mutants of MAP3K7/TAK1, MAP2K4/MKK4, and MAP2K7/MKK7, which suggests that this kinase may function through the MAP3K7-MAP2K4-MAP2K7 kinase cascade, and mediate the TNF-alpha signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T71367-Ag-1Human MAP4K4 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T71367-Ag-1Rat MAP4K4 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T71367-Ag-1Mouse MAP4K4 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T71367-Ag-1Cynomolgus/ Rhesus macaque MAP4K4 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T71367-Ag-1Feline MAP4K4 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T71367-Ag-1Canine MAP4K4 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T71367-Ag-1Bovine MAP4K4 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T71367-Ag-1Equine MAP4K4 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T71367-Ag, GM-Tg-rg-T71367-Ag, GM-Tg-mg-T71367-Ag, GM-Tg-cynog-T71367-Ag,
GM-Tg-felg-T71367-Ag, GM-Tg-cang-T71367-Ag, GM-Tg-bovg-T71367-Ag, GM-Tg-equg-T71367-Ag-1
Products Name MAP4K4 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameMAP4K4
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MAP4K4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.