Recombinant multi-species DPYD/ DHP/ DHPDHASE protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to DPYD/DPYD products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DPYD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: DPYD, gene name: DPYD, also named as DHP, DHPDHASE, DPD. The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T75890-Ag-1Human DPYD proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T75890-Ag-1Rat DPYD proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T75890-Ag-1Mouse DPYD proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T75890-Ag-1Cynomolgus/ Rhesus macaque DPYD proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T75890-Ag-1Feline DPYD proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T75890-Ag-1Canine DPYD proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T75890-Ag-1Bovine DPYD proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T75890-Ag-1Equine DPYD proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T75890-Ag, GM-Tg-rg-T75890-Ag, GM-Tg-mg-T75890-Ag, GM-Tg-cynog-T75890-Ag,
GM-Tg-felg-T75890-Ag, GM-Tg-cang-T75890-Ag, GM-Tg-bovg-T75890-Ag, GM-Tg-equg-T75890-Ag-1
Products Name DPYD protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameDPYD
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DPYD protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.