Recombinant multi-species PGTB1/ GGTase-I/ PGGT1B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GGTase-I/PGGT1B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: GGTase-I, gene name: PGGT1B, also named as BGGI, GGTI. Protein geranylgeranyltransferase type I (GGTase-I) transfers a geranylgeranyl group to the cysteine residue of candidate proteins containing a C-terminal CAAX motif in which 'A' is an aliphatic amino acid and 'X' is leucine (summarized by Zhang et al., 1994 [PubMed 8106351]). The enzyme is composed of a 48-kD alpha subunit (FNTA; MIM 134635) and a 43-kD beta subunit, encoded by the PGGT1B gene. The FNTA gene encodes the alpha subunit for both GGTase-I and the related enzyme farnesyltransferase.[supplied by OMIM, Mar 2010].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T76396-Ag-1Human GGTase-I/PGGT1B proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T76396-Ag-1Rat GGTase-I/PGGT1B proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T76396-Ag-1Mouse GGTase-I/PGGT1B proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T76396-Ag-1Cynomolgus/ Rhesus macaque GGTase-I/PGGT1B proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T76396-Ag-1Feline GGTase-I/PGGT1B proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T76396-Ag-1Canine GGTase-I/PGGT1B proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T76396-Ag-1Bovine GGTase-I/PGGT1B proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T76396-Ag-1Equine GGTase-I/PGGT1B proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T76396-Ag, GM-Tg-rg-T76396-Ag, GM-Tg-mg-T76396-Ag, GM-Tg-cynog-T76396-Ag,
GM-Tg-felg-T76396-Ag, GM-Tg-cang-T76396-Ag, GM-Tg-bovg-T76396-Ag, GM-Tg-equg-T76396-Ag-1
Products Name GGTase-I/PGGT1B protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameGGTase-I
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine GGTase-I/PGGT1B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.