Recombinant multi-species PNPH/ PNP/ NP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to PNP/PNP products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PNP protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PNP, gene name: PNP, also named as NP, PRO1837, PUNP. This gene encodes an enzyme which reversibly catalyzes the phosphorolysis of purine nucleosides. The enzyme is trimeric, containing three identical subunits. Mutations which result in nucleoside phosphorylase deficiency result in defective T-cell (cell-mediated) immunity but can also affect B-cell immunity and antibody responses. Neurologic disorders may also be apparent in patients with immune defects. A known polymorphism at aa position 51 that does not affect enzyme activity has been described. A pseudogene has been identified on chromosome 2. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T78198-Ag-1Human PNP proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T78198-Ag-1Rat PNP proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T78198-Ag-1Mouse PNP proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T78198-Ag-1Cynomolgus/ Rhesus macaque PNP proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T78198-Ag-1Feline PNP proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T78198-Ag-1Canine PNP proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T78198-Ag-1Bovine PNP proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T78198-Ag-1Equine PNP proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T78198-Ag, GM-Tg-rg-T78198-Ag, GM-Tg-mg-T78198-Ag, GM-Tg-cynog-T78198-Ag,
GM-Tg-felg-T78198-Ag, GM-Tg-cang-T78198-Ag, GM-Tg-bovg-T78198-Ag, GM-Tg-equg-T78198-Ag-1
Products Name PNP protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NamePNP
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PNP protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.