Recombinant multi-species TYK2/ IMD35/ JTK1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TYK2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: TYK2, gene name: TYK2, also named as IMD35, JTK1. This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also a component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with Immunodeficiency 35. [provided by RefSeq, Sep 2020].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T78932-Ag-1Human TYK2 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T78932-Ag-1Rat TYK2 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T78932-Ag-1Mouse TYK2 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T78932-Ag-1Cynomolgus/ Rhesus macaque TYK2 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T78932-Ag-1Feline TYK2 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T78932-Ag-1Canine TYK2 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T78932-Ag-1Bovine TYK2 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T78932-Ag-1Equine TYK2 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T78932-Ag, GM-Tg-rg-T78932-Ag, GM-Tg-mg-T78932-Ag, GM-Tg-cynog-T78932-Ag,
GM-Tg-felg-T78932-Ag, GM-Tg-cang-T78932-Ag, GM-Tg-bovg-T78932-Ag, GM-Tg-equg-T78932-Ag-1
Products Name TYK2 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameTYK2
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TYK2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.