Recombinant multi-species VHL/ HRCA1/ RCA11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to VHL/VHL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine VHL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: VHL, gene name: VHL, also named as HRCA1, RCA11, pVHL, VHL. This gene encodes a component of a ubiquitination complex. The encoded protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. In addition to oxygen-related gene expression, this protein plays a role in many other cellular processes including cilia formation, cytokine signaling, regulation of senescence, and formation of the extracellular matrix. Variants of this gene are associated with von Hippel-Lindau syndrome, pheochromocytoma, erythrocytosis, renal cell carcinoma, and cerebellar hemangioblastoma. [provided by RefSeq, Jun 2022].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T80423-Ag-1Human VHL proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T80423-Ag-1Rat VHL proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T80423-Ag-1Mouse VHL proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T80423-Ag-1Cynomolgus/ Rhesus macaque VHL proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T80423-Ag-1Feline VHL proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T80423-Ag-1Canine VHL proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T80423-Ag-1Bovine VHL proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T80423-Ag-1Equine VHL proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T80423-Ag, GM-Tg-rg-T80423-Ag, GM-Tg-mg-T80423-Ag, GM-Tg-cynog-T80423-Ag,
GM-Tg-felg-T80423-Ag, GM-Tg-cang-T80423-Ag, GM-Tg-bovg-T80423-Ag, GM-Tg-equg-T80423-Ag-1
Products Name VHL protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameVHL
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine VHL protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.