Recombinant multi-species INS/ IDDM/ IDDM1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine INS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: INS, gene name: INS, also named as IDDM, IDDM1, IDDM2, ILPR, IRDN, MODY10. This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes diabetes mellitus, maturity-onset diabetes of the young type 10 and hyperproinsulinemia. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq, May 2020].

Order information

* GeneMedi provides NON-PROFIT PRICE to support Academic research.Please click inquiry for product quotation. → Inquiry

Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T82841-Ag-1	Human INS protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T82841-Ag-1	Rat INS protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T82841-Ag-1	Mouse INS protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T82841-Ag-1	Cynomolgus/ Rhesus macaque INS protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T82841-Ag-1	Feline INS protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T82841-Ag-1	Canine INS protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T82841-Ag-1	Bovine INS protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T82841-Ag-1	Equine INS protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T82841-Ag, GM-Tg-rg-T82841-Ag, GM-Tg-mg-T82841-Ag, GM-Tg-cynog-T82841-Ag, GM-Tg-felg-T82841-Ag, GM-Tg-cang-T82841-Ag, GM-Tg-bovg-T82841-Ag, GM-Tg-equg-T82841-Ag-1
Products Name	INS protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	INS
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine INS protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.