Recombinant multi-species CSN5/ COPS5/ JAB1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to COPS5/COPS5 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COPS5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: COPS5, gene name: COPS5, also named as CSN5, JAB1, MOV-34, SGN5. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of  cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T84791-Ag-1Human COPS5 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T84791-Ag-1Rat COPS5 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T84791-Ag-1Mouse COPS5 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T84791-Ag-1Cynomolgus/ Rhesus macaque COPS5 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T84791-Ag-1Feline COPS5 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T84791-Ag-1Canine COPS5 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T84791-Ag-1Bovine COPS5 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T84791-Ag-1Equine COPS5 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T84791-Ag, GM-Tg-rg-T84791-Ag, GM-Tg-mg-T84791-Ag, GM-Tg-cynog-T84791-Ag,
GM-Tg-felg-T84791-Ag, GM-Tg-cang-T84791-Ag, GM-Tg-bovg-T84791-Ag, GM-Tg-equg-T84791-Ag-1
Products Name COPS5 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameCOPS5
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine COPS5 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.