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Recombinant multi-species BRD2/ BRD2-IT1/ D6S113E protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Go to BRD2/BRD2 products collection >>Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BRD2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
The target: BRD2, gene name: BRD2, also named as BRD2-IT1, D6S113E, FSH, FSRG1, NAT, O27.1.1, RING3, RNF3. This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010].
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| Catalog No. | Product Name | Species | Size | Price |
| GM-Tg-hg-T86399-Ag-1 | Human BRD2 protein | Human | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-rg-T86399-Ag-1 | Rat BRD2 protein | Rat | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-mg-T86399-Ag-1 | Mouse BRD2 protein | Mouse | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cynog-T86399-Ag-1 | Cynomolgus/ Rhesus macaque BRD2 protein | Cynomolgus/ Rhesus macaque | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-felg-T86399-Ag-1 | Feline BRD2 protein | Feline | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-cang-T86399-Ag-1 | Canine BRD2 protein | Canine | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-bovg-T86399-Ag-1 | Bovine BRD2 protein | Bovine | 1mg/10mg/100mg/≥100mg | Inquiry |
| GM-Tg-bovg-T86399-Ag-1 | Equine BRD2 protein | Equine | 1mg/10mg/100mg/≥100mg | Inquiry |
| Shipping Cost: | 760.00 | |||
Description
| Catalog No. | GM-Tg-hg-T86399-Ag, GM-Tg-rg-T86399-Ag, GM-Tg-mg-T86399-Ag, GM-Tg-cynog-T86399-Ag, GM-Tg-felg-T86399-Ag, GM-Tg-cang-T86399-Ag, GM-Tg-bovg-T86399-Ag, GM-Tg-equg-T86399-Ag-1 |
| Products Name | BRD2 protein |
| Species | Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine |
| Target Name | BRD2 |
| Protein Sub-location | Introcelluar Protein |
| Isotypes | Recombinant protein |
| Expression platform | Mammalian cell |
| Bioactivity validation | Affintiy&bioactivity validated by ELISA, cell culture validated. |
| Tag | His |
| Products description | Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BRD2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research. |
| Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
