Recombinant multi-species LONM/ LONP1/ CODASS protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

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(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LONP1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: LONP1, gene name: LONP1, also named as CODASS, LON, LONP, LonHS, PIM1, PRSS15, hLON. This gene encodes a mitochondrial matrix protein that belongs to the Lon family of ATP-dependent proteases. This protein mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides in the mitochondrial matrix. It may also have a chaperone function in the assembly of inner membrane protein complexes, and participate in the regulation of mitochondrial gene expression and maintenance of the integrity of the mitochondrial genome. Decreased expression of this gene has been noted in a patient with hereditary spastic paraplegia (PMID:18378094). Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Feb 2013].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T86773-Ag-1Human LONP1 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T86773-Ag-1Rat LONP1 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T86773-Ag-1Mouse LONP1 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T86773-Ag-1Cynomolgus/ Rhesus macaque LONP1 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T86773-Ag-1Feline LONP1 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T86773-Ag-1Canine LONP1 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T86773-Ag-1Bovine LONP1 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T86773-Ag-1Equine LONP1 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T86773-Ag, GM-Tg-rg-T86773-Ag, GM-Tg-mg-T86773-Ag, GM-Tg-cynog-T86773-Ag,
GM-Tg-felg-T86773-Ag, GM-Tg-cang-T86773-Ag, GM-Tg-bovg-T86773-Ag, GM-Tg-equg-T86773-Ag-1
Products Name LONP1 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameLONP1
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine LONP1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.