Recombinant multi-species NODAL/ HTX5 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to NODAL/NODAL products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NODAL protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: NODAL, gene name: NODAL, also named as HTX5. This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which regulates early embryonic development. This protein is required for maintenance of human embryonic stem cell pluripotency and may play a role in human placental development. Mutations in this gene are associated with heterotaxy, a condition characterized by random orientation of visceral organs with respect to the left-right axis. [provided by RefSeq, Aug 2016].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T87448-Ag-1Human NODAL proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T87448-Ag-1Rat NODAL proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T87448-Ag-1Mouse NODAL proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T87448-Ag-1Cynomolgus/ Rhesus macaque NODAL proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T87448-Ag-1Feline NODAL proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T87448-Ag-1Canine NODAL proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T87448-Ag-1Bovine NODAL proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T87448-Ag-1Equine NODAL proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T87448-Ag, GM-Tg-rg-T87448-Ag, GM-Tg-mg-T87448-Ag, GM-Tg-cynog-T87448-Ag,
GM-Tg-felg-T87448-Ag, GM-Tg-cang-T87448-Ag, GM-Tg-bovg-T87448-Ag, GM-Tg-equg-T87448-Ag-1
Products Name NODAL protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameNODAL
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NODAL protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.