Recombinant multi-species DOT1L/ HLNM/ DOT1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to HLNM/DOT1L products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HLNM/DOT1L protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: HLNM, gene name: DOT1L, also named as DOT1, KMT4. The protein encoded by this gene is a histone methyltransferase that methylates lysine-79 of histone H3. It is inactive against free core histones, but shows significant histone methyltransferase activity against nucleosomes. [provided by RefSeq, Aug 2011].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T87686-Ag-1Human HLNM/DOT1L proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T87686-Ag-1Rat HLNM/DOT1L proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T87686-Ag-1Mouse HLNM/DOT1L proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T87686-Ag-1Cynomolgus/ Rhesus macaque HLNM/DOT1L proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T87686-Ag-1Feline HLNM/DOT1L proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T87686-Ag-1Canine HLNM/DOT1L proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T87686-Ag-1Bovine HLNM/DOT1L proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T87686-Ag-1Equine HLNM/DOT1L proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-T87686-Ag, GM-Tg-rg-T87686-Ag, GM-Tg-mg-T87686-Ag, GM-Tg-cynog-T87686-Ag,
GM-Tg-felg-T87686-Ag, GM-Tg-cang-T87686-Ag, GM-Tg-bovg-T87686-Ag, GM-Tg-equg-T87686-Ag-1
Products Name HLNM/DOT1L protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameHLNM
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HLNM/DOT1L protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.