Recombinant multi-species DEFM/ PDF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PDF, gene name: PDF, also named as . Protein synthesis proceeds after formylation of methionine by methionyl-tRNA formyl transferase (FMT) and transfer of the charged initiator f-met tRNA to the ribosome. In eubacteria and eukaryotic organelles the product of this gene, peptide deformylase (PDF), removes the formyl group from the initiating methionine of nascent peptides. In eubacteria, deformylation of nascent peptides is required for subsequent cleavage of initiating methionines by methionine aminopeptidase. The discovery that a natural inhibitor of PDF, actinonin, acts as an antimicrobial agent in some bacteria has spurred intensive research into the design of bacterial-specific PDF inhibitors. In human cells, only mitochondrial proteins have N-formylation of initiating methionines. Protein inhibitors of PDF or siRNAs of PDF block the growth of cancer cell lines but have no effect on normal cell growth. In humans, PDF function may therefore be restricted to rapidly growing cells. [provided by RefSeq, Nov 2008].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T89515-Ag-1	Human PDF protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T89515-Ag-1	Rat PDF protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T89515-Ag-1	Mouse PDF protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T89515-Ag-1	Cynomolgus/ Rhesus macaque PDF protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T89515-Ag-1	Feline PDF protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T89515-Ag-1	Canine PDF protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T89515-Ag-1	Bovine PDF protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T89515-Ag-1	Equine PDF protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T89515-Ag, GM-Tg-rg-T89515-Ag, GM-Tg-mg-T89515-Ag, GM-Tg-cynog-T89515-Ag, GM-Tg-felg-T89515-Ag, GM-Tg-cang-T89515-Ag, GM-Tg-bovg-T89515-Ag, GM-Tg-equg-T89515-Ag-1
Products Name	PDF protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	PDF
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDF protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.