Recombinant multi-species ESR1/ ESR/ ER protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ESR/ESR1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: ESR, gene name: ESR1, also named as ER, ESR, ESRA, ESTRR, Era, NR3A1. This gene encodes an estrogen receptor and ligand-activated transcription factor. The canonical protein contains an N-terminal ligand-independent transactivation domain, a central DNA binding domain, a hinge domain, and a C-terminal ligand-dependent transactivation domain. The protein localizes to the nucleus where it may form either a homodimer or a heterodimer with estrogen receptor 2. The protein encoded by this gene regulates the transcription of many estrogen-inducible genes that play a role in growth, metabolism, sexual development, gestation, and other reproductive functions and is expressed in many non-reproductive tissues. The receptor encoded by this gene plays a key role in breast cancer, endometrial cancer, and osteoporosis. This gene is reported to have dozens of transcript variants due to the use of alternate promoters and alternative splicing, however, the full-length nature of many of these variants remain uncertain. [provided by RefSeq, Jul 2020].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T89534-Ag-1	Human ESR/ESR1 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T89534-Ag-1	Rat ESR/ESR1 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T89534-Ag-1	Mouse ESR/ESR1 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T89534-Ag-1	Cynomolgus/ Rhesus macaque ESR/ESR1 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T89534-Ag-1	Feline ESR/ESR1 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T89534-Ag-1	Canine ESR/ESR1 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T89534-Ag-1	Bovine ESR/ESR1 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T89534-Ag-1	Equine ESR/ESR1 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T89534-Ag, GM-Tg-rg-T89534-Ag, GM-Tg-mg-T89534-Ag, GM-Tg-cynog-T89534-Ag, GM-Tg-felg-T89534-Ag, GM-Tg-cang-T89534-Ag, GM-Tg-bovg-T89534-Ag, GM-Tg-equg-T89534-Ag-1
Products Name	ESR/ESR1 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	ESR
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ESR/ESR1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.