Recombinant multi-species RAE1/ CHM/ DXS540 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CHM protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: CHM, gene name: CHM, also named as DXS540, GGTA, HSD-32, REP-1, TCD. This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2016].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T90628-Ag-1	Human CHM protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T90628-Ag-1	Rat CHM protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T90628-Ag-1	Mouse CHM protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T90628-Ag-1	Cynomolgus/ Rhesus macaque CHM protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T90628-Ag-1	Feline CHM protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T90628-Ag-1	Canine CHM protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T90628-Ag-1	Bovine CHM protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T90628-Ag-1	Equine CHM protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T90628-Ag, GM-Tg-rg-T90628-Ag, GM-Tg-mg-T90628-Ag, GM-Tg-cynog-T90628-Ag, GM-Tg-felg-T90628-Ag, GM-Tg-cang-T90628-Ag, GM-Tg-bovg-T90628-Ag, GM-Tg-equg-T90628-Ag-1
Products Name	CHM protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	CHM
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine CHM protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.