Recombinant multi-species TIE1/ JTK14/ TIE protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to TIE1/TIE1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TIE1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: TIE1, gene name: TIE1, also named as JTK14, TIE. This gene encodes a member of the tyrosine protein kinase family. The encoded protein plays a critical role in angiogenesis and blood vessel stability by inhibiting angiopoietin 1 signaling through the endothelial receptor tyrosine kinase Tie2. Ectodomain cleavage of the encoded protein relieves inhibition of Tie2 and is mediated by multiple factors including vascular endothelial growth factor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T98539-Ag-1Human TIE1 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T98539-Ag-1Rat TIE1 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T98539-Ag-1Mouse TIE1 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T98539-Ag-1Cynomolgus/ Rhesus macaque TIE1 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T98539-Ag-1Feline TIE1 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T98539-Ag-1Canine TIE1 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T98539-Ag-1Bovine TIE1 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T98539-Ag-1Equine TIE1 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T98539-Ag, GM-Tg-rg-T98539-Ag, GM-Tg-mg-T98539-Ag, GM-Tg-cynog-T98539-Ag,
GM-Tg-felg-T98539-Ag, GM-Tg-cang-T98539-Ag, GM-Tg-bovg-T98539-Ag, GM-Tg-equg-T98539-Ag-1
Products Name TIE1 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameTIE1
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine TIE1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.