Recombinant multi-species THB/ THRB/ C-ERBA-2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine THRB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: THRB, gene name: THRB, also named as C-ERBA-2, C-ERBA-BETA, ERBA2, GRTH, NR1A2, PRTH, THR11, THRB2, THRB. The protein encoded by this gene is a nuclear hormone receptor for triiodothyronine. It is one of the several receptors for thyroid hormone, and has been shown to mediate the biological activities of thyroid hormone. Knockout studies in mice suggest that the different receptors, while having certain extent of redundancy, may mediate different functions of thyroid hormone. Mutations in this gene are known to be a cause of generalized thyroid hormone resistance (GTHR), a syndrome characterized by goiter and high levels of circulating thyroid hormone (T3-T4), with normal or slightly elevated thyroid stimulating hormone (TSH). Several alternatively spliced transcript variants encoding the same protein have been observed for this gene. [provided by RefSeq, Jul 2008].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T98933-Ag-1	Human THRB protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T98933-Ag-1	Rat THRB protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T98933-Ag-1	Mouse THRB protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T98933-Ag-1	Cynomolgus/ Rhesus macaque THRB protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T98933-Ag-1	Feline THRB protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T98933-Ag-1	Canine THRB protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T98933-Ag-1	Bovine THRB protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T98933-Ag-1	Equine THRB protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T98933-Ag, GM-Tg-rg-T98933-Ag, GM-Tg-mg-T98933-Ag, GM-Tg-cynog-T98933-Ag, GM-Tg-felg-T98933-Ag, GM-Tg-cang-T98933-Ag, GM-Tg-bovg-T98933-Ag, GM-Tg-equg-T98933-Ag-1
Products Name	THRB protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	THRB
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine THRB protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.