Recombinant multi-species BRAF/ B-RAF1/ B-raf1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BRAF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: BRAF, gene name: BRAF, also named as B-RAF1, B-raf1, NS7, RAFB1, BRAF. This gene encodes a protein belonging to the RAF family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERK signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene, most commonly the V600E mutation, are the most frequently identified cancer-causing mutations in melanoma, and have been identified in various other cancers as well, including non-Hodgkin lymphoma, colorectal cancer, thyroid carcinoma, non-small cell lung carcinoma, hairy cell leukemia and adenocarcinoma of lung. Mutations in this gene are also associated with cardiofaciocutaneous, Noonan, and Costello syndromes, which exhibit overlapping phenotypes. A pseudogene of this gene has been identified on the X chromosome. [provided by RefSeq, Aug 2017].

Order information

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T99089-Ag-1	Human BRAF protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T99089-Ag-1	Rat BRAF protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T99089-Ag-1	Mouse BRAF protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T99089-Ag-1	Cynomolgus/ Rhesus macaque BRAF protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T99089-Ag-1	Feline BRAF protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T99089-Ag-1	Canine BRAF protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T99089-Ag-1	Bovine BRAF protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T99089-Ag-1	Equine BRAF protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T99089-Ag, GM-Tg-rg-T99089-Ag, GM-Tg-mg-T99089-Ag, GM-Tg-cynog-T99089-Ag, GM-Tg-felg-T99089-Ag, GM-Tg-cang-T99089-Ag, GM-Tg-bovg-T99089-Ag, GM-Tg-equg-T99089-Ag-1
Products Name	BRAF protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	BRAF
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine BRAF protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.