Recombinant multi-species TPO/ THPO/ MGDF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine THPO protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: THPO, gene name: THPO, also named as MGDF, MKCSF, ML, MPLLG, THCYT1, TPO. Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent. [provided by RefSeq, Feb 2014].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T99379-Ag-1	Human THPO protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T99379-Ag-1	Rat THPO protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T99379-Ag-1	Mouse THPO protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T99379-Ag-1	Cynomolgus/ Rhesus macaque THPO protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T99379-Ag-1	Feline THPO protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T99379-Ag-1	Canine THPO protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T99379-Ag-1	Bovine THPO protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T99379-Ag-1	Equine THPO protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T99379-Ag, GM-Tg-rg-T99379-Ag, GM-Tg-mg-T99379-Ag, GM-Tg-cynog-T99379-Ag, GM-Tg-felg-T99379-Ag, GM-Tg-cang-T99379-Ag, GM-Tg-bovg-T99379-Ag, GM-Tg-equg-T99379-Ag-1
Products Name	THPO protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	THPO
Protein Sub-location	Secreted Protein/Potential Cytokines
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine THPO protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.