Recombinant multi-species STA5A/ STAT5A/ MGF protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine STAT5A protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: STAT5A, gene name: STAT5A, also named as MGF, STAT5. The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Dec 2013].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-TA046-Ag-1	Human STAT5A protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-TA046-Ag-1	Rat STAT5A protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-TA046-Ag-1	Mouse STAT5A protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-TA046-Ag-1	Cynomolgus/ Rhesus macaque STAT5A protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-TA046-Ag-1	Feline STAT5A protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-TA046-Ag-1	Canine STAT5A protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-TA046-Ag-1	Bovine STAT5A protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-TA046-Ag-1	Equine STAT5A protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-TA046-Ag, GM-Tg-rg-TA046-Ag, GM-Tg-mg-TA046-Ag, GM-Tg-cynog-TA046-Ag, GM-Tg-felg-TA046-Ag, GM-Tg-cang-TA046-Ag, GM-Tg-bovg-TA046-Ag, GM-Tg-equg-TA046-Ag-1
Products Name	STAT5A protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	STAT5A
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine STAT5A protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.