Recombinant multi-species DPOE2/ POLE2/ DPE2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to POLE2/POLE2 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine POLE2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: POLE2, gene name: POLE2, also named as DPE2. DNA polymerase epsilon, which is involved in DNA repair and replication, is composed of a large catalytic subunit and a small accessory subunit. The protein encoded by this gene represents the small subunit (B). Defects in this gene have been linked to colorectal cancer and to combined immunodeficiency. [provided by RefSeq, Jan 2017].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-TA186-Ag-1Human POLE2 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-TA186-Ag-1Rat POLE2 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-TA186-Ag-1Mouse POLE2 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-TA186-Ag-1Cynomolgus/ Rhesus macaque POLE2 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-TA186-Ag-1Feline POLE2 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-TA186-Ag-1Canine POLE2 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-TA186-Ag-1Bovine POLE2 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-TA186-Ag-1Equine POLE2 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-TA186-Ag, GM-Tg-rg-TA186-Ag, GM-Tg-mg-TA186-Ag, GM-Tg-cynog-TA186-Ag,
GM-Tg-felg-TA186-Ag, GM-Tg-cang-TA186-Ag, GM-Tg-bovg-TA186-Ag, GM-Tg-equg-TA186-Ag-1
Products Name POLE2 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NamePOLE2
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine POLE2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.