Equine Spirochaeta antibody and antigen (recombinant protein)

Diagnostic anti-Equine Spirochaeta antibodies pairs and antigen for animal health (animal Equine/Horse) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Target products collectionGo to Equine disease testing products collection >>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-EQU-Spirochaeta-Ag01Equine Spirochaeta$3090.00
GMP-EQU-Spirochaeta-Ab01Anti-Equine Spirochaeta mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-Spirochaeta-Ab02Anti-Equine Spirochaeta mouse monoclonal antibody (mAb)$3090.00
GMP-EQU-Spirochaeta-Ab03Anti-Equine Spirochaeta human monoclonal antibody (mAb)$3090.00
GMP-EQU-Spirochaeta-Ab04Anti-Equine Spirochaeta human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-EQU-Spirochaeta-Ag01
Product NameEquine Spirochaeta
Target/BiomarkerEquine Spirochaeta
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Equine Spirochaeta antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Spirochaeta level test of animal Equine/Horse.
TagHis
Reconized/Reactive SpecicsEquine Spirochaeta
Product descriptionRecombinant Equine Spirochaeta protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-Spirochaeta-Ab01,GMP-EQU-Spirochaeta-Ab02
Target/BiomarkerEquine Spirochaeta
Product NameAnti-Equine Spirochaeta mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Equine Spirochaeta antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine Spirochaeta antibodies in Equine Spirochaeta level test of animal Equine/Horse.
Product descriptionAnti-Equine Spirochaeta mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine Spirochaeta antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-EQU-Spirochaeta-Ab03,GMP-EQU-Spirochaeta-Ab04
Target/BiomarkerEquine Spirochaeta
Product NameAnti-Equine Spirochaeta human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Equine Spirochaeta antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine Spirochaeta antibodies in Equine Spirochaeta level test of animal Equine/Horse.
Product descriptionAnti-Equine Spirochaeta mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information




    In horses, Spirochaeta refers to a group of bacteria within the phylum Spirochaetes, which are known for their distinctive spiral shape and unique mode of movement. These bacteria can cause various diseases in horses, although not all spirochetes are pathogenic. Here’s an overview of some conditions associated with spirochetes in equine health:

    Lyme Disease

    Cause: Lyme disease in horses, as in humans and dogs, is caused by the bacterium Borrelia burgdorferi and transmitted by the bite of infected Ixodes ticks.

    Symptoms: Symptoms in horses can be nonspecific and include stiffness, lameness due to joint inflammation, muscle tenderness, fever, and lethargy. Some horses may also exhibit behavioral changes or neurologic signs.

    Diagnosis: Diagnosis is often based on clinical signs, a history of tick exposure, serological testing for antibodies against Borrelia burgdorferi, and response to treatment.

    Treatment: The treatment typically involves antibiotics such as doxycycline or minocycline. Early diagnosis and treatment can lead to better outcomes.

    Prevention: Preventive measures include tick control strategies, such as regular tick checks and management of pasture and paddock areas to reduce tick populations.

    Leptospirosis

    Cause: Caused by bacteria of the genus Leptospira, leptospirosis is less commonly diagnosed in horses than in dogs but can occur. Horses can become infected through contact with urine-contaminated water or soil, or through placental transfer from the mare to the foal.

    Symptoms: Symptoms can vary and include fever, jaundice, anorexia, abortion in pregnant mares, and uveitis (moon blindness), one of the most recognized complications in horses.

    Diagnosis: Diagnosis involves serological tests to detect antibodies against Leptospira spp.

    Treatment: Treatment includes antibiotics, such as penicillin or doxycycline, and supportive care.

    Prevention: Preventive measures include vaccination and minimizing exposure to areas where the bacteria may be present in standing water.

    Digital Dermatitis

    Association: While more commonly associated with cattle, spirochetes similar to those implicated in bovine digital dermatitis have been identified in cases of equine digital dermatitis, a condition affecting the skin around the hooves.

    Symptoms: Lesions and lameness are common symptoms.

    Treatment: Treatment involves topical antiseptics and antibiotics.

    Diagnosis and Treatment

    Diagnosis of spirochetal infections in horses may include serological tests, PCR assays, culture methods, and microscopic examination of blood or tissue samples.

    Treatment generally involves the use of appropriate antibiotics, based on the specific spirochete involved and the disease being treated. Supportive care is also important.

    Prevention

    Tick Control: Effective tick control and management of the environment to reduce tick populations are crucial for preventing Lyme disease.

    Vaccination: Where available, vaccination against leptospirosis can help prevent infection.

    Environmental Management: Reducing exposure to potentially contaminated water sources can help prevent leptospirosis.

    Spirochetal infections in horses can pose significant health challenges but can be managed with appropriate veterinary care. Understanding the risks and implementing preventive measures are key to maintaining equine health.



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