Vibrio cholerae (cytotoxin B (CtxB)) antibody and antigen (Recombinant protein)

Diagnostic antibodies (anti-Vibrio cholerae, anti-cytotoxin B?(CtxB)) and antigens (recombinant protein) for Infectious disease cytotoxin B?(CtxB) detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.

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Product information

Catalog No. Description US $ Price (per mg)
GMP-IVD-P035-Tg001-Ag01 Recombinant human Vibrio cholerae (V. cholerae) cytotoxin B?(CtxB) Protein 3090
GMP-IVD-P035-Tg001-Ab01 Anti-human Vibrio cholerae (V. cholerae) cytotoxin B?(CtxB) mouse monoclonal antibody (mAb) 1953
GMP-IVD-P035-Tg001-Ab02 Anti-human Vibrio cholerae (V. cholerae) cytotoxin B?(CtxB) mouse monoclonal antibody (mAb) 1953
GMP-IVD-P035-Tg001-Ab03 Anti-human Vibrio cholerae (V. cholerae) cytotoxin B?(CtxB) human monoclonal antibody (mAb) 1953
GMP-IVD-P035-Tg001-Ab04 Anti-human Vibrio cholerae (V. cholerae) cytotoxin B?(CtxB) human monoclonal antibody (mAb) 1953

Size: 1mg | 10mg | 100mg



Product Description

Cat No. of Products GMP-IVD-P035-Tg001-Ag01
Product Name Recombinant human Vibrio cholerae (V. cholerae) cytotoxin B?(CtxB) Protein
Pathogen Vibrio cholerae
Target/Biomarker Vibrio cholerae(cytotoxin B (CtxB))
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Vibrio cholerae (cytotoxin B (CtxB)) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in cytotoxin B (CtxB) level test of Infectious disease (Cholera) and related syndrome evaluation.
Tag His
Products description Recombinant human Vibrio cholerae (V. cholerae) cytotoxin B?(CtxB) Protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-IVD-P035-Tg001-Ab01, GMP-IVD-P035-Tg001-Ab02
Product Name Anti-human Vibrio cholerae (V. cholerae) cytotoxin B?(CtxB) mouse monoclonal antibody (mAb)
Pathogen Vibrio cholerae
Target/Biomarker Vibrio cholerae(cytotoxin B (CtxB))
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Human Vibrio cholerae (cytotoxin B (CtxB)) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Vibrio cholerae (cytotoxin B (CtxB)) antibodies in cytotoxin B (CtxB) level test of Infectious disease (Cholera) and related syndrome evaluation.
Tag mFc
Products description Anti-human Vibrio cholerae (V. cholerae) cytotoxin B?(CtxB) mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-IVD-P035-Tg001-Ab03, GMP-IVD-P035-Tg001-Ab04
Product Name Anti-human Vibrio cholerae (V. cholerae) cytotoxin B?(CtxB) human monoclonal antibody (mAb)
Pathogen Vibrio cholerae
Target/Biomarker Vibrio cholerae(cytotoxin B (CtxB))
Expression platform CHO
Isotypes Human IgG1
Bioactivity validation Human Vibrio cholerae (cytotoxin B (CtxB)) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Vibrio cholerae (cytotoxin B (CtxB)) antibodies in cytotoxin B (CtxB) level test of Infectious disease (Cholera) and related syndrome evaluation.
Tag hFc
Products description Anti-human Vibrio cholerae (V. cholerae) cytotoxin B?(CtxB) human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Validation Data


    Evidence has shown activated osteoclasts create resorption pits with low pH to dissolve the inorganic matrix and lysomal enzymes, such as TRAP and cathepsin K, effectively digest the exposed type-1 collagen releasing specific degradation products, such as the carboxyl-terminal cross-linked telopeptides of type I collagen (CTX-1). The biomarker β-CTx offers significant information on bone metabolism (bone remodeling) and is useful to predict fracture risk and to monitor the treatment efficacy. Recently, our R&D department demonstrated that our GMP-h-β-CTx-Ab pairs have a large linear range and good sensitivity against the GMP-h-β-CTx-Ag01. Below is the result of GeneMedi's GMP-h-β-CTx-Ab01/02/03/04 (Anti-human β-CTx mouse monoclonal antibody) validation with GMP-h-β-CTx-Ag01 (Recombinant human β-CTx Protein) in ELISA. We highly recommend the Ab01-Ab02 pair and Ag to you.

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    Figure 1. GeneMedi's GMP-h-β-CTx-Ab01/02/03/04 (Anti-human β-CTx mouse monoclonal antibody) are validated to detect the GMP-h-β-CTx-Ag01 (Recombinant human β-CTx Protein) in ELISA.

       EC50 [Ab01 (capture)-Ab02 (detect) ]= 271.3 ppb;

       EC50 [Ab01 (capture)-Ab04 (detect)]= 614.8 ppb;

       EC50 [Ab03 (capture)-Ab02 (detect) ]= 363.5 ppb;

       EC50 [Ab03 (capture)-Ab04 (detect) ]= 811.8 ppb.

    Click to get more Data / Case study about the product.



    Target/Biomarker information

    Cholera is?an acute diarrheal illness caused by infection of the intestine with Vibrio cholerae bacteria. People can get sick when they swallow food or water contaminated with cholera bacteria. The infection is often mild or without symptoms, but can sometimes be severe and life-threatening.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.

    Comments


    Richard Lopez 2024-01-19 00:48:08
    The antigen is quite stable with high quality data to be used in Chemiluminescent Immunoassay (CLIA). It fosters provision of accurate diagnostic results.

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