Tramadol (TRA) antibody and antigen (hapten, BSA/OVA conjugated)

Product information

Catalog No.	Description	US $ Price (per mg)
GMP-SMT-245-Ag01	BSA-Tramadol (TRA)	$756.00
GMP-SMT-245-Ag02	OVA-Tramadol (TRA)	$756.00
GMP-SMT-245-Ab01	Anti-human Tramadol (TRA) mouse monoclonal antibody (mAb)	$1953.00
GMP-SMT-245-Ab02	Anti-human Tramadol (TRA) human monoclonal antibody (mAb)	$1953.00

Size： 1mg | 10mg | 100mg

Product Description

BSA-Tramadol (TRA)

Cat No.	GMP-SMT-245-Ag01
Product Name	BSA-Tramadol (TRA)
Target	Tramadol (TRA)
Expression platform	Synthetic
Bioactivity validation	Tramadol (TRA) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in TRA level test of Pain and related syndrome evaluation
Products description	Competitive immunoassay-validated hapten-carrier conjugates BSA-Tramadol (TRA) / OVA-Tramadol (TRA) is Synthetic.
Purity	High (TBD)
Application	Competitive immunoassay validation (Competitive ELISA), ELISA, Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

OVA-Tramadol (TRA)

Cat No.	GMP-SMT-245-Ag02
Product Name	OVA-Tramadol (TRA)
Target	Tramadol (TRA)
Expression platform	Synthetic
Bioactivity validation	Tramadol (TRA) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in TRA level test of Pain and related syndrome evaluation
Products description	Competitive immunoassay-validated hapten-carrier conjugates BSA-Tramadol (TRA) / OVA-Tramadol (TRA) is Synthetic.
Purity	High (TBD)
Application	Competitive immunoassay validation (Competitive ELISA), ELISA, Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Anti-human Tramadol (TRA) mouse monoclonal antibody (mAb)

Cat No.	GMP-SMT-245-Ab01
Product Name	Anti-human Tramadol (TRA) mouse monoclonal antibody (mAb)
Target	Tramadol (TRA)
Expression platform	hybridoma
Isotypes	Mouse IgG
Bioactivity validation	Tramadol (TRA) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Tramadol (TRA) antibodies in TRA level test of Pain and related syndrome evaluation.
Tag	mFc
Products description	Anti-human Tramadol (TRA) mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology.
Purity	High (TBD)
Application	Competitive immunoassay validation (Competitive ELISA), ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Anti-human Tramadol (TRA) human monoclonal antibody (mAb)

Cat No.	GMP-SMT-245-Ab02
Product Name	Anti-human Tramadol (TRA) human monoclonal antibody (mAb)
Target	Tramadol (TRA)
Expression platform	hybridoma
Isotypes	Human IgG1
Bioactivity validation	Tramadol (TRA) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Tramadol (TRA) antibodies in TRA level test of Pain and related syndrome evaluation.
Tag	hFc
Products description	Anti-human Tramadol (TRA) mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO.
Purity	Purity: ≥95% （SDS-PAGE）
Application	Competitive immunoassay validation (Competitive ELISA), ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

What is Tramadol and Its Role in In Vitro Diagnosis (IVD)?

Tramadol, a synthetic opioid analgesic, is widely prescribed for the management of moderate to severe pain. It exerts its pharmacological effects by binding to μ-opioid receptors in the central nervous system and inhibiting the reuptake of serotonin and norepinephrine. This dual mechanism of action contributes to its analgesic efficacy and makes it a valuable therapeutic option for various pain conditions, including acute and chronic pain syndromes.

In the context of in vitro diagnosis (IVD), Tramadol serves as a crucial target molecule for precise detection and quantification in biological samples. Accurate measurement of Tramadol levels is essential for several diagnostic applications, including therapeutic drug monitoring, forensic toxicology, and pharmacokinetic studies. Our company specializes in providing high-quality antibodies and small molecule competitive antigens specifically designed for Tramadol detection, ensuring reliable and reproducible results in laboratory settings.

Why Measure Tramadol?

The measurement of Tramadol levels offers valuable insights and benefits across multiple domains:

Clinical Management: Tramadol is commonly used in clinical practice for pain management in diverse patient populations. Monitoring Tramadol levels enables healthcare providers to optimize treatment regimens, adjust dosage parameters, and assess patient response to therapy. This personalized approach to pain management helps maximize therapeutic efficacy while minimizing the risk of adverse effects and opioid-related complications.

Therapeutic Drug Monitoring (TDM): Therapeutic drug monitoring of Tramadol is essential for maintaining optimal drug concentrations within the therapeutic range. By monitoring Tramadol levels in patients receiving chronic opioid therapy, healthcare providers can ensure adherence to treatment protocols, prevent drug toxicity, and identify individuals at risk of therapeutic failure or opioid misuse.

Forensic Investigations: In forensic toxicology, the measurement of Tramadol levels in biological specimens such as blood, urine, or hair samples provides crucial information for determining drug exposure, assessing compliance with prescribed medication regimens, and investigating drug-related incidents, including drug overdoses, poisonings, and impaired driving cases.

Research and Development: Quantification of Tramadol levels contributes to ongoing research efforts aimed at elucidating its pharmacokinetic properties, exploring potential drug interactions, and investigating novel therapeutic applications. By studying Tramadol metabolism, distribution, and elimination patterns, researchers can improve our understanding of opioid pharmacology and develop innovative strategies for pain management and opioid stewardship.

Public Health Surveillance: Surveillance of Tramadol usage patterns and associated adverse events informs public health policies, regulatory decisions, and interventions aimed at promoting safe medication practices and preventing opioid-related harms. By monitoring Tramadol utilization trends, regulatory agencies can identify emerging issues, implement targeted interventions, and monitor the impact of regulatory measures on opioid prescribing practices and patient outcomes.

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