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Description of Small molecules (Chemicals, Antibiotics,Mycotoxins,Hormones,Drugs of Abuse, etc.)

Cyclosporin A is a cyclic nonribosomal peptide of eleven amino acids; an immunosuppressant drug widely used in post-allogeneic organ transplant to reduce the activity of the patient's immune system, and therefore the risk of organ rejection. Also causes reversible inhibition of immunocompetent lymphocytes in the G0- and G1-phase of the cell cycle. It has a role as an antifungal agent, an antirheumatic drug, a dermatologic drug, an immunosuppressive agent, a metabolite, a carcinogenic agent, an anti-asthmatic drug, an EC 3.1.3.16 (phosphoprotein phosphatase) inhibitor and an anticoronaviral agent.

Cyclosporin a appears as white prismatic needles (from acetone) or white powder. (NTP, 1992)

Cyclosporine is a natural cyclic polypeptide immunosuppressant isolated from the fungus Beauveria nivea. The exact mechanism of action of cyclosporine is not known but may involve binding to the cellular protein cytophilin, resulting in inhibition of the enzyme calcineurin. This agent appears to specifically and reversibly inhibit immunocompetent lymphocytes in the G0-or G1-phase of the cell cycle. T-lymphocytes are preferentially inhibited with T-helper cells as the primary target. Cyclosporine also inhibits lymphokine production and release. (NCI04)

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Catalog No. Description Price(In USD) Qty (Quantity) Sum(In USD)
GMP-SMT-71-1 1. BSA-Cyclosporin A; Size:1mg
2. Anti-Cyclosporin A mouse monoclonal antibody; Size:1mg
1365
GMP-SMT-71-1 1. BSA-Cyclosporin A; Size:10mg
2. Anti-Cyclosporin A mouse monoclonal antibody; Size:10mg
9555
GMP-SMT-71-1 1. BSA-Cyclosporin A; Size:100mg
2. Anti-Cyclosporin A mouse monoclonal antibody; Size:100mg
66885
GMP-SMT-71-2 1. OVA-Cyclosporin A; Size:1mg
2. Anti-Cyclosporin A mouse monoclonal antibody; Size:1mg
1365
GMP-SMT-71-2 1. OVA-Cyclosporin A; Size:10mg
2. Anti-Cyclosporin A mouse monoclonal antibody; Size:10mg
9555
GMP-SMT-71-2 1. OVA-Cyclosporin A; Size:100mg
2. Anti-Cyclosporin A mouse monoclonal antibody; Size:100mg
66885
GMP-SMT-71-Ab-1 Anti-Cyclosporin A mouse monoclonal antibody; Size:1mg 1043
GMP-SMT-71-Ab-1 Anti-Cyclosporin A mouse monoclonal antibody; Size:10mg 7301
GMP-SMT-71-Ab-1 Anti-Cyclosporin A mouse monoclonal antibody; Size:100mg 51107
GMP-SMT-71-Ag-1 BSA-Cyclosporin A; Size:1mg 756
GMP-SMT-71-Ag-1 BSA-Cyclosporin A; Size:10mg 5292
GMP-SMT-71-Ag-1 BSA-Cyclosporin A; Size:100mg 37044
GMP-SMT-71-Ag-2 OVA-Cyclosporin A; Size:1mg 756
GMP-SMT-71-Ag-2 OVA-Cyclosporin A; Size:10mg 5292
GMP-SMT-71-Ag-2 OVA-Cyclosporin A; Size:100mg 37044
GMP-SMT-71 ≥100mg Inquiry
Shipping Cost: 760.00
Total:



Description


BSA-Cyclosporin A

Cat No. GMP-SMT-71-Ag-1
Bioactivity validation Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products description Competitive immunoassay-validated hapten-carrier conjugates [BSA-Cyclosporin A)]with anti-Hapten antibody. The hapten hapten-carrier conjugates [BSA-Cyclosporin A)] had been validated with our anti-Hapten antibody[Anti-Cyclosporin A mouse monoclonal antibody] via competitive ELISA test.
Application ELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


OVA-Cyclosporin A

Cat No. GMP-SMT-71-Ag-2
Bioactivity validation Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products description Competitive immunoassay-validated hapten-carrier conjugates [ OVA-Cyclosporin A)] with anti-Hapten antibody. The hapten hapten-carrier conjugates[ OVA-Cyclosporin A)] had been validated with our anti-Hapten antibody[Anti-Cyclosporin A mouse monoclonal antibody] via competitive ELISA test.
Application ELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Cyclosporin A mouse monoclonal antibody

Cat No. GMP-SMT-71-Ab-1
Host of Antibody Mouse IgG
Bioactivity validation Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb) 0.1-0.2
Products description The anti-Hapten antibody against hapten [Cyclosporin A)] had beenvalidated with our hapten hapten-carrier conjugates [BSA-Cyclosporin A)] via competitive ELISA test.
Application ELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.