Recombinant multi-species PGS2/ DCN/ CSCD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to DCN/DCN products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DCN protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: DCN, gene name: DCN, also named as CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B. This gene encodes a member of the small leucine-rich proteoglycan family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protein. This protein plays a role in collagen fibril assembly. Binding of this protein to multiple cell surface receptors mediates its role in tumor suppression, including a stimulatory effect on autophagy and inflammation and an inhibitory effect on angiogenesis and tumorigenesis. This gene and the related gene biglycan are thought to be the result of a gene duplication. Mutations in this gene are associated with congenital stromal corneal dystrophy in human patients. [provided by RefSeq, Nov 2015].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-T67883-Ag-1Human DCN proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-T67883-Ag-1Rat DCN proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-T67883-Ag-1Mouse DCN proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-T67883-Ag-1Cynomolgus/ Rhesus macaque DCN proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-T67883-Ag-1Feline DCN proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-T67883-Ag-1Canine DCN proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T67883-Ag-1Bovine DCN proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-T67883-Ag-1Equine DCN proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-T67883-Ag, GM-Tg-rg-T67883-Ag, GM-Tg-mg-T67883-Ag, GM-Tg-cynog-T67883-Ag,
GM-Tg-felg-T67883-Ag, GM-Tg-cang-T67883-Ag, GM-Tg-bovg-T67883-Ag, GM-Tg-equg-T67883-Ag-1
Products Name DCN protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameDCN
Protein Sub-locationSecreted Protein/Potential Cytokines
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine DCN protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.