Recombinant multi-species MP2K2/ MEK2/ MAP2K2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MEK2/MAP2K2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: MEK2, gene name: MAP2K2, also named as CFC4, MAPKK2, MEK2, MKK2, PRKMK2. The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, cognitive disability, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene. [provided by RefSeq, Jul 2008].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-T89055-Ag-1	Human MEK2/MAP2K2 protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-T89055-Ag-1	Rat MEK2/MAP2K2 protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-T89055-Ag-1	Mouse MEK2/MAP2K2 protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-T89055-Ag-1	Cynomolgus/ Rhesus macaque MEK2/MAP2K2 protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-T89055-Ag-1	Feline MEK2/MAP2K2 protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-T89055-Ag-1	Canine MEK2/MAP2K2 protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T89055-Ag-1	Bovine MEK2/MAP2K2 protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-T89055-Ag-1	Equine MEK2/MAP2K2 protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-T89055-Ag, GM-Tg-rg-T89055-Ag, GM-Tg-mg-T89055-Ag, GM-Tg-cynog-T89055-Ag, GM-Tg-felg-T89055-Ag, GM-Tg-cang-T89055-Ag, GM-Tg-bovg-T89055-Ag, GM-Tg-equg-T89055-Ag-1
Products Name	MEK2/MAP2K2 protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	MEK2
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine MEK2/MAP2K2 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.