Pre-made Acapatamab benchmark antibody ( Bispecific scFv, anti-FOLH1/GCPII;CD3E therapeutic antibody, Anti-FGCP/GCP2/NAALAD1/PSM/PSMA/mGCP;T3E/TCRE/IMD18 Antibody) for drug discovery and mechanism of action (MOA) research

Pre-Made Acapatamab biosimilar, Bispecific scFv, Anti-FOLH1/GCPII;CD3E Antibody: Anti-FGCP/GCP2/NAALAD1/PSM/PSMA/mGCP;T3E/TCRE/IMD18 therapeutic antibody is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Acapatamab (formerly AMG 160) is a half-life extended (HLE) anti- prostate-specific membrane antigen (PSMA) x anti-CD3 BiTE (bispecific T cell engager) molecule. It is being investigated for the treatment of non-small cell lung cancer (NSCLC).

Order information

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Catalog No.	Package	Price(In USD)	Qty (Quantity)	Sum(In USD)
GMP-Bios-ab-006-1mg	1mg	Inquiry
GMP-Bios-ab-006-10mg	10mg	Inquiry
GMP-Bios-ab-006-100mg	100mg	Inquiry
GMP-Bios-ab-006-xmg	≥100mg	Inquiry
			Shipping Cost:	760.00
			Total:

Description

Products Name (INN Index)	Pre-Made Acapatamab biosimilar, Bispecific scFv, Anti-FOLH1/GCPII;CD3E Antibody: Anti-FGCP/GCP2/NAALAD1/PSM/PSMA/mGCP;T3E/TCRE/IMD18 therapeutic antibody
INN Name	Acapatamab
Target	GCPII;CD3E
Format	Bispecific scFv
Derivation	Bispecific antibody
Species Reactivity	Human
CH1 Isotype	IgG1
VD LC	Kappa;Lambda
Highest_Clin_Trial (Jan '20)	Phase-I/II
Est. Status	Active
100% SI Structure	None;None
99% SI Structure	None;None
95-98% SI Structure	None;None
Year Proposed	2020
Year Recommended	2021
Companies	Amgen
Conditions Approved	na
Conditions Active	Cancers;Prostrate cancer;Metastatic cancer
Conditions Discontinued	na
Development Tech	BiTE Technology