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Anti-IL6 therapeutic antibody (Pre-made Siltuximab biosimilar,Whole mAb) is a biosimilar expressed by mammalian cell line as a benchmark reference therapeutic antibody for biological drug disovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Siltuximab (INN, trade name Sylvant; also known as CNTO 328, anti-IL-6 chimeric monoclonal antibody or cCLB8) is a chimeric (made from human and mouse proteins) monoclonal antibody. It binds to interleukin-6. Siltuximab has been investigated for the treatment of neoplastic diseases: metastatic renal cell cancer, prostate cancer, and Castleman's disease, among other types of cancer.

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Delivery impact due to the Coronavirus Outbreak

With the COVID-19 outbreak in the world, many flights have been cancelled. In order for the customer to receive the goods properly, we use the FedEx Customized Freight (FCF) of Fedex which demands a higher fee. If the delivery fee is more expensive in your area, we will contact you by mail.

Catalog No. Package Price(In USD) Qty (Quantity) Sum(In USD)
GMP-Bios-ab-520-1mg 1mg 3090
GMP-Bios-ab-520-10mg 10mg 21890
GMP-Bios-ab-520-100mg 100mg 148000
GMP-Bios-ab-520-xmg >100mg Inquiry
Shipping Cost: 760.00


Products Name (INN Index) Anti-IL6 therapeutic antibody (Pre-made Siltuximab biosimilar,Whole mAb)
INN Name Siltuximab
FormatWhole mAb
DerivationChimeric (Mouse/Human)
Species ReactivityHuman
CH1 IsotypeIgG1
VD LCKappa
Highest_Clin_Trial (Jan '20)Approved
Est. StatusActive
100% SI StructureNone
99% SI StructureNone
95-98% SI StructureNone
Year Proposed2008
Year Recommended2009
CompaniesCentocor Inc;Janssen Biotech;Memorial Sloan-Kettering Cancer Center
Conditions ApprovedGiant lymph node hyperplasia
Conditions ActiveMultiple myeloma
Conditions DiscontinuedParaproteinaemia;Myelodysplastic syndromes;Non-Hodgkin's lymphoma;Prostate cancer;Renal cell carcinoma
Development Techna