Canine Spirochaeta antibody and antigen (recombinant protein)

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Diagnostic anti-Canine Spirochaeta antibodies pairs and antigen for animal health (animal Dog/Canine) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product Description

Reference

Validation Data

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Target/Biomarker Information

In dogs (canines), the term "Spirochaeta" refers to bacteria from the phylum Spirochaetes, which are characterized by their unique spiral shape and distinctive method of movement. These bacteria can cause a variety of diseases in dogs, with some of the most notable being caused by specific genera such as Leptospira, Borrelia, and Treponema. Here’s an overview of the diseases associated with these spirochetes in dogs:

Leptospirosis

Cause: Caused by bacteria from the genus Leptospira, leptospirosis is a significant concern in canine health. It is a zoonotic disease, meaning it can be transmitted from animals to humans.

Transmission: Dogs can contract the bacteria from contaminated water sources, soil, or through direct contact with the urine of infected animals.

Symptoms: Can range from mild to severe and include fever, vomiting, abdominal pain, diarrhea, refusal to eat, severe weakness and lethargy, stiffness, jaundice, muscle pain, infertility, and kidney or liver failure.

Treatment: Involves antibiotics and supportive care. Early diagnosis and treatment are crucial for recovery.

Prevention: Vaccination against certain strains of Leptospira is available and recommended, especially in areas where the disease is common.

Lyme Disease

Cause: Caused by the bacterium Borrelia burgdorferi, transmitted to dogs through the bite of infected Ixodes ticks (deer ticks).

Symptoms: Include fever, lameness due to inflammation of the joints, swollen lymph nodes, lethargy, and loss of appetite. Not all infected dogs will show symptoms.

Treatment: Typically involves antibiotics like doxycycline. Early treatment usually results in rapid improvement.

Prevention: Preventative measures include tick control products and vaccines against Lyme disease, along with regular tick checks.

Canine Spirochetosis (Periodontal Disease)

Cause: Spirochetes, including members of the genus Treponema, have been implicated in periodontal disease in dogs, contributing to gum infection and tooth decay.

Symptoms: Bad breath, plaque build-up, inflamed gums, and tooth loss. It can lead to more serious health issues if bacteria enter the bloodstream.

Treatment: Includes professional dental cleaning and may require tooth extractions or other periodontal treatments.

Prevention: Regular dental care, including brushing the dog's teeth and using dental chews, along with professional cleanings, can help prevent periodontal disease.

Diagnosis and Treatment

Diagnosis of spirochetal infections generally involves serological testing, PCR assays, microscopic examination, and sometimes culture of the organism.

Treatment varies depending on the disease but often includes the use of specific antibiotics effective against spirochetes, supportive care for symptoms, and preventive measures to avoid exposure to the pathogens.

Prevention

Vaccination against leptospirosis and Lyme disease is available and recommended in areas where these diseases are prevalent.

Tick Control is crucial for preventing Lyme disease and other tick-borne illnesses.

Environmental Management and hygiene can help reduce the risk of leptospirosis by avoiding stagnant water and controlling rodent populations.

Dental Care is essential for preventing periodontal disease caused by spirochetes among other bacteria.

Spirochetal infections in dogs can be serious but are often manageable with prompt veterinary care. Prevention through vaccination, tick control, and good hygiene practices is key to keeping dogs healthy and reducing the risk of these infections.

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