Feline Spirochaeta antibody and antigen (recombinant protein)

Diagnostic anti-Feline Spirochaeta antibodies pairs and antigen for animal health (animal Cat/Feline) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-Spirochaeta-Ag01Feline Spirochaeta$3090.00
GMP-FEL-Spirochaeta-Ab01Anti-Feline Spirochaeta mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-Spirochaeta-Ab02Anti-Feline Spirochaeta mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-Spirochaeta-Ab03Anti-Feline Spirochaeta human monoclonal antibody (mAb)$3090.00
GMP-FEL-Spirochaeta-Ab04Anti-Feline Spirochaeta human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-Spirochaeta-Ag01
Product NameFeline Spirochaeta
Target/BiomarkerFeline Spirochaeta
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline Spirochaeta antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Spirochaeta level test of animal Cat/Feline.
TagHis
Reconized/Reactive SpecicsFeline Spirochaeta
Product descriptionRecombinant Feline Spirochaeta protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-Spirochaeta-Ab01,GMP-FEL-Spirochaeta-Ab02
Target/BiomarkerFeline Spirochaeta
Product NameAnti-Feline Spirochaeta mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline Spirochaeta antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline Spirochaeta antibodies in Feline Spirochaeta level test of animal Cat/Feline.
Product descriptionAnti-Feline Spirochaeta mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline Spirochaeta antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-Spirochaeta-Ab03,GMP-FEL-Spirochaeta-Ab04
Target/BiomarkerFeline Spirochaeta
Product NameAnti-Feline Spirochaeta human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline Spirochaeta antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline Spirochaeta antibodies in Feline Spirochaeta level test of animal Cat/Feline.
Product descriptionAnti-Feline Spirochaeta mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    Spirochetes are a group of motile bacteria, characterized by their unique helical shape, which allows them to move in a corkscrew motion. In cats (felines), spirochetes can be associated with various health conditions, although they are not as commonly reported in cats as in other species. One of the more well-known spirochetal infections in animals and humans is caused by the Borrelia species, which is responsible for Lyme disease, but direct involvement in feline health with this particular spirochete is relatively rare due to cats' apparent resistance to Lyme disease symptoms.

    Common Spirochetal Infections in Cats

    Leptospirosis: While leptospirosis is primarily known to affect dogs, cats can also be exposed to Leptospira spp., the bacteria responsible for this disease. However, cats often appear to be resistant to leptospirosis, or they may be asymptomatic carriers. The disease in mammals generally causes kidney and liver issues, but confirmed cases in cats are rare, and they are not considered a major reservoir for the bacteria.

    Periodontal Disease: Certain spirochetes have been implicated in periodontal disease in cats, as part of the complex bacterial community that contributes to oral infections. These bacteria can contribute to the plaque that leads to gingivitis and periodontitis.

    Diagnosis and Treatment

    Diagnosis: Diagnosing spirochetal infections in cats can involve serological tests, PCR (Polymerase Chain Reaction) assays, and microscopic examination of samples from affected tissues. For periodontal disease, a clinical examination supported by dental X-rays can help identify the extent of the problem.

    Treatment: Treatment for spirochetal infections may include antibiotics that are effective against these types of bacteria. For leptospirosis, although rare in cats, supportive care and treatment with appropriate antibiotics can be effective. Managing periodontal disease involves dental cleaning, possibly under anesthesia, and may require tooth extractions in severe cases.

    Prevention

    Preventive measures for spirochetal infections include controlling exposure to environments where leptospirosis could be contracted (more relevant for dogs than cats) and maintaining good oral hygiene to prevent periodontal disease. Regular veterinary check-ups are important for early detection and management of these and other health issues.

    In summary, while spirochetes can affect cats, the impact and prevalence of specific spirochetal diseases like leptospirosis are less significant in cats than in other animals. Nonetheless, awareness of the potential for these infections and proper veterinary care can help manage and prevent health issues associated with spirochetes in feline populations.



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