Peanut agglutinin(PNA) antibody/antigen (BSA/OVA/KLH conjugated hapten)

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anti-Peanut agglutinin(PNA) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Size： 1mg | 10mg | 100mg

Product Description

BSA-Peanut agglutinin(PNA)

OVA-Peanut agglutinin(PNA)

Anti-Peanut agglutinin(PNA) mouse monoclonal antibody

Anti-Peanut agglutinin(PNA) human monoclonal antibody

Reference

Validation Data

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Biomarker Information

1. Peanut Agglutinin (PNA): An Immunological Probe for Peanut Allergens

Scientific Description:



Peanut agglutinin (PNA) stands as a meticulously engineered monoclonal antibody, meticulously crafted by our biopharmaceutical company. This specialized antibody serves as a vital tool within the realm of allergen analysis, particularly in relation to peanut allergies.

Role in Allergens:



PNA, the result of precise scientific development, assumes a critical role in the accurate assessment of peanut allergens within diverse sample matrices. The hallmark of PNA lies in its selective binding affinity towards specific epitopes present in peanut allergenic constituents. As such, it plays a pivotal role in enabling the sensitive and specific detection and quantification of these allergens in various contexts, including food products, environmental samples, and clinical specimens.

Beyond its diagnostic utility, PNA significantly contributes to the advancement of our understanding of peanut allergies. Owing to its exceptional specificity and high affinity, PNA permits a comprehensive exploration of the mechanisms underlying allergic responses to peanuts. By dissecting these intricate processes at the molecular level, PNA provides invaluable insights into the pathophysiology of peanut allergies. Consequently, it serves as an instrumental tool in the development of enhanced diagnostic methodologies and potential therapeutic interventions aimed at mitigating the adverse effects of peanut allergies.

To delve deeper into the role of PNA in allergens, it is essential to understand its molecular interactions with peanut allergenic components. PNA targets specific carbohydrate structures, such as N-acetylgalactosamine and N-acetylglucosamine, present on the surface of peanut allergens. These carbohydrate structures are critical in eliciting immune responses in individuals with peanut allergies. PNA's selective binding to these epitopes allows for the precise identification and quantification of peanut allergens, making it an indispensable tool for allergen detection.

2. Quantifying Peanut Agglutinin (PNA): Imperatives and Applications

Scientific Explanation:

The quantification of Peanut agglutinin (PNA) is a scientific imperative, grounded in several compelling rationales:

a. Allergen Detection: PNA, characterized by its exquisite specificity for peanut allergens, empowers the precise identification of peanut allergenic components. This capability is pivotal in guaranteeing the safety of individuals with peanut allergies by enabling the identification of potential allergen contamination in food products and environmental samples.

b. Advancing Scientific Frontiers: PNA, as an invaluable tool, propels scientific exploration into peanut allergies. Its application facilitates the meticulous study of the presence and concentration of peanut allergens, thereby fostering a deeper comprehension of the molecular underpinnings of allergic reactions. This, in turn, catalyzes the development of enhanced diagnostic assays and prospective therapeutic strategies.

c. Quality Assurance: Industries involved in food processing and manufacturing rely on PNA quantification to ensure stringent quality control. By verifying the absence or presence of peanut allergens, companies uphold compliance with allergen labeling regulations, thus safeguarding consumer health.

d. Clinical Pertinence: In clinical settings, PNA quantification assumes significance in diagnosing peanut allergies and monitoring patient responses to allergy interventions. Accurate assessment of PNA levels in patient samples furnishes critical insights into the course and management of peanut allergies.

To comprehend the significance of quantifying PNA in allergen detection, one must appreciate its role as an immunological probe in clinical and research contexts. PNA's utility is predicated on its capability to selectively bind to peanut allergens, enabling their precise identification and quantification. This is achieved through immunoassays, wherein PNA is employed as a primary reagent to capture peanut allergens from complex sample matrices. Subsequent detection methods, such as enzyme-linked immunosorbent assays (ELISA) or fluorescence-based techniques, facilitate the quantitative assessment of allergen concentrations.

In scientific research, PNA quantification aids in elucidating the intricate dynamics of peanut allergens. Researchers can employ PNA to explore the presence and concentration of allergens in various samples, including those derived from natural sources, processed foods, or environmental sources. This granular understanding is paramount in unraveling the underlying mechanisms of peanut allergies, including the role of specific allergenic proteins in triggering immune responses.

Furthermore, PNA's significance extends to quality control within the food industry. Manufacturers and processors utilize PNA quantification to rigorously monitor their products for the presence of peanut allergens. This is crucial for complying with stringent allergen labeling regulations and ensuring consumer safety. PNA-based assays provide a reliable means of confirming the absence of peanut allergens or detecting potential cross-contamination, safeguarding individuals with peanut allergies from inadvertent exposure.

In clinical settings, the quantification of PNA assumes a pivotal role in diagnosing and managing peanut allergies. By measuring PNA levels in patient samples, healthcare practitioners can determine the severity of allergies and monitor the efficacy of allergy treatments. This quantitative approach allows for a more precise assessment of patients' immune responses to peanut allergens, aiding in treatment optimization and personalized care.

In conclusion, the quantification of Peanut agglutinin (PNA) serves multifaceted purposes encompassing allergen detection, scientific exploration, quality assurance, and clinical applications. Its role as an immunological probe, with its selective binding affinity for peanut allergens, empowers researchers, clinicians, and industries to better understand, manage, and mitigate the challenges posed by peanut allergies, ultimately enhancing the safety and well-being of affected individuals.

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