Zearalenone / Zearalenol antibody/antigen (BSA/OVA/KLH conjugated hapten)

 Download 

anti-Zearalenone / Zearalenol antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

Go to Mycotoxins diagnostics products collection >>

Product information

Size： 1mg | 10mg | 100mg

Product Description

BSA-Zearalenone / Zearalenol

OVA-Zearalenone / Zearalenol

Anti-Zearalenone / Zearalenol mouse monoclonal antibody

Anti-Zearalenone / Zearalenol human monoclonal antibody

Reference

Validation Data

Click to get more Data / Case study about the product.

Biomarker Information

Zearalenone/Zearalenol and Their Role in Mycotoxins

Zearalenone (ZEN) and Zearalenol (ZOL) are mycotoxins, a class of secondary metabolites produced by certain molds, particularly strains of the Fusarium genus. These mycotoxins have garnered significant attention due to their widespread presence in agricultural commodities, primarily grains and cereals, posing potential risks to both human health and animal agriculture. Understanding the intricate role of ZEN and ZOL in the realm of mycotoxins is essential for comprehending their impact and devising effective strategies for mitigating their adverse effects.

1.1. Zearalenone (ZEN):

Zearalenone is a nonsteroidal estrogenic mycotoxin characterized by its structural similarity to the hormone estrogen. As a result, ZEN has the potential to exert estrogenic effects in both animals and humans. It is primarily produced by Fusarium species during the contamination of crops in the field or during storage. ZEN contamination in agricultural products, particularly in grains, raises significant concerns due to its potential impact on reproductive health and endocrine disruption, particularly in livestock such as pigs and cattle. It can lead to reproductive disorders, including hyperestrogenism, fertility issues, and compromised animal well-being.

1.2. Zearalenol (ZOL):

Zearalenol is a metabolite of ZEN, formed when ZEN is ingested and subsequently metabolized by animals or humans. Like its precursor, ZOL exhibits estrogenic properties, contributing to the overall estrogenic burden in biological systems. Consequently, ZOL can exacerbate the estrogenic effects initiated by ZEN, intensifying the risks associated with mycotoxin exposure.

In the context of mycotoxins, ZEN and ZOL are recognized as significant contaminants, meriting comprehensive investigation and monitoring due to their potential adverse effects on food safety, animal health, and regulatory compliance.

2. Why Measure Zearalenone/Zearalenol?

The measurement of ZEN and ZOL is instrumental for various scientific, regulatory, and practical reasons:

2.1. Food Safety (Serial Number 2.1):

Accurate quantification of ZEN and ZOL is pivotal to ensure food safety. Contamination of food products, especially grains and cereals, with these mycotoxins can have severe health implications for consumers. Regulatory agencies set maximum allowable levels (MRLs) for ZEN and ZOL in food products to protect public health. Rigorous measurement ensures compliance with these safety regulations, preventing the distribution of contaminated products that may pose health risks, including estrogenic effects, to consumers.

2.2. Animal Health (Serial Number 2.2):

In the livestock and animal farming industries, the quality and safety of animal feed are paramount. Contaminated feed can lead to adverse effects on animal health and reproductive performance. Measuring ZEN and ZOL levels is crucial for identifying contaminated feed batches, allowing for timely intervention to safeguard animal well-being and reproductive outcomes.

2.3. Regulatory Compliance (Serial Number 2.3):

Many countries and regions have established stringent regulations governing the presence of ZEN and ZOL in food and feed products. These regulations include setting maximum allowable limits. Regular measurement and monitoring are essential to ensure compliance with these legal requirements, preventing potential legal consequences for food and feed producers and distributors.

2.4. Quality Control (Serial Number 2.4):

Quality control protocols in the food and feed industries encompass the measurement of mycotoxin levels, including ZEN and ZOL. Accurate and reliable measurement methods are integral to maintaining product quality and brand integrity. Consistent quality control procedures are necessary to detect and eliminate contaminated product batches, thereby upholding the reputation of the brand and ensuring consumer safety.

2.5. Research and Development (Serial Number 2.5):

Scientific research plays a pivotal role in understanding the toxicological mechanisms and impacts of ZEN and ZOL. Accurate measurement of these mycotoxins is fundamental to advancing scientific knowledge, enabling the development of mitigation strategies, and exploring potential interventions. Researchers use precise measurement techniques to investigate the molecular pathways and physiological effects associated with ZEN and ZOL exposure.

2.6. Risk Assessment (Serial Number 2.6):

Comprehensive risk assessments within food and feed supply chains require thorough data on mycotoxin contamination. Measurement of ZEN and ZOL contributes to evaluating health risks associated with their presence and assists in devising effective risk management strategies. This includes identifying potential sources of contamination, implementing control measures, and ensuring the safety of products along the supply chain.

In summary, ZEN and ZOL are pivotal subjects of study in the field of mycotoxins due to their widespread presence and potential health risks. Precise measurement of these mycotoxins is indispensable for ensuring food safety, protecting animal health, complying with regulatory standards, maintaining product quality, advancing scientific knowledge, and conducting thorough risk assessments within the agricultural and food industries. Robust and reliable measurement methodologies are fundamental for addressing these multifaceted concerns effectively.

About GDU