Paromomycin antibody/antigen (BSA/OVA/KLH conjugated hapten)

anti-Paromomycin antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-SMT-20-11. BSA-Paromomycin
2. Anti-Paromomycin mouse monoclonal antibody
$2709.00
GMP-SMT-20-21. OVA-Paromomycin
2. Anti-Paromomycin mouse monoclonal antibody
$2709.00
GMP-SMT-20-31. BSA-Paromomycin
2. Anti-Paromomycin human monoclonal antibody
$2709.00
GMP-SMT-20-41. OVA-Paromomycin
2. Anti-Paromomycin human monoclonal antibody
$2709.00
GMP-SMT-20-Ag-1BSA-Paromomycin$756.00
GMP-SMT-20-Ag-2OVA-Paromomycin$756.00
GMP-SMT-20-Ab-1Anti-Paromomycin mouse monoclonal antibody$1953.00
GMP-SMT-20-Ab-2Anti-Paromomycin human monoclonal antibody$1953.00

Size: 1mg | 10mg | 100mg



Product Description


BSA-Paromomycin

Cat No.GMP-SMT-20-Ag-1
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates BSA-Paromomycin with anti-Hapten antibody. The hapten hapten-carrier conjugates BSA-Paromomycin had been validated with our anti-Hapten antibody Anti-Paromomycin mouse monoclonal antibody via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


OVA-Paromomycin

Cat No.GMP-SMT-20-Ag-2
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates OVA-Paromomycin with anti-Hapten antibody. The hapten hapten-carrier conjugates OVA-Paromomycin had been validated with our anti-Hapten antibody Anti-Paromomycin mouse monoclonal antibody via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Paromomycin mouse monoclonal antibody

Cat No.GMP-SMT-20-Ab-1
Host of AntibodyMouse IgG
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)1.00
Products descriptionThe anti-Hapten antibody against hapten Paromomycin had been validated with our hapten hapten-carrier conjugates BSA-Paromomycin via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Paromomycin human monoclonal antibody

Cat No.GMP-SMT-20-Ab-2
Host of AntibodyHuman IgG1
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)1.00
Products descriptionThe anti-Hapten antibody against hapten Paromomycin had been validated with our hapten hapten-carrier conjugates BSA-Paromomycin via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study


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    Biomarker Information


    1. Neomycin in Veterinary Medicine:

    Neomycin is an aminoglycoside antibiotic that holds a crucial role in the field of veterinary medicine. Aminoglycosides are a class of antibiotics known for their effectiveness against a wide range of gram-negative bacteria. Neomycin, as one of these antibiotics, is employed in veterinary medicine to treat and prevent bacterial infections in animals. It is used across various animal species, including livestock (such as cattle, poultry, and swine) and companion animals (like dogs and cats). Veterinarians commonly use neomycin to combat bacterial infections in animals, making it an essential tool in the veterinarian's arsenal.

    Neomycin's mechanism of action involves inhibiting protein synthesis in bacteria, which ultimately leads to their death. This antibiotic is particularly effective against bacteria that are resistant to other classes of antibiotics, making it a valuable option for treating bacterial infections in animals.

    2. Food Safety and Residues:

    The use of antibiotics, including neomycin, in animal feed has raised concerns about the potential presence of drug residues in animal-derived food products. When animals consume feed containing neomycin, traces of the antibiotic may accumulate in their tissues, including muscle (meat), milk, and eggs. This necessitates stringent monitoring and control measures to ensure food safety and safeguard human health.

    The presence of excessive antibiotic residues in food products poses several risks. First, it can contribute to the development of antibiotic resistance in bacteria. This resistance can then be transferred to humans who consume these contaminated animal products, potentially reducing the effectiveness of antibiotics in treating human infections. Second, excessive antibiotic residues in food items can lead to adverse health effects in consumers, including allergic reactions and other side effects.

    3. Regulatory Compliance:

    To address the concerns regarding antibiotic residues in food products, regulatory authorities have established Maximum Residue Limits (MRLs). MRLs are specific concentration limits for individual drugs or their metabolites allowed in animal-derived food products. These limits are set to ensure that the consumption of these products does not pose a risk to human health.

    Monitoring and measuring neomycin levels in animal-derived food products are essential to ensure compliance with these MRLs. If products exceed the established MRLs, it can result in legal issues for producers, including product recalls, fines, or even criminal charges. Additionally, violations of MRLs can damage the reputation of the food industry and pose substantial risks to consumer health.

    4. Safety and Quality Assurance:

    The meticulous monitoring of neomycin levels in animal-derived food products is a cornerstone of maintaining the safety and quality of these commodities. It is an integral part of the broader food safety system. Ensuring that these products are devoid of excessive neomycin residues upholds the integrity of the food supply chain and safeguards consumer health.

    In addition to regulatory requirements, many producers and manufacturers implement their own quality control measures to assure the absence of antibiotic residues in their products. These may include rigorous testing, quality assurance programs, and adherence to best practices in animal husbandry and food processing.

    5. Animal Feed Additive:

    Beyond its therapeutic use, neomycin also serves as an additive in animal feed. This application is aimed at enhancing animal growth and optimizing feed efficiency, particularly in modern animal husbandry practices. When included in animal feed, neomycin can promote the growth of livestock and improve their feed utilization, leading to more efficient production.

    Accurate measurement of neomycin in animal feed is essential to ensure that animals receive the precise dosage required for growth promotion and disease prevention. This precise dosing helps optimize the growth of animals, reduce the cost of production, and minimize the use of other resources, such as feed and water.

    In conclusion, neomycin plays a multifaceted and significant role in veterinary medicine, food safety, regulatory compliance, and as an animal feed additive. Its effectiveness in treating bacterial infections in animals is balanced by the need to monitor and control its presence in animal-derived food products to protect human health. The establishment of Maximum Residue Limits and adherence to quality assurance measures ensure that neomycin is used safely and responsibly, both as a therapeutic agent and a growth-promoting additive in animal husbandry.



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