Nitrazepam, Clonazepam(CZP) antibody and antigen (hapten, BSA/OVA conjugated)

Diagnostic anti-Nitrazepam, Clonazepam (CZP) antibodies (anti-Nitrazepam, Clonazepam, anti-CZP) and diagnostic hapten-carrier conjugates BSA-Nitrazepam, Clonazepam (CZP), OVA-Nitrazepam, Clonazepam (CZP), KLH-Nitrazepam, Clonazepam (CZP) antigens for Epilepsy CZP detection in ELISA test, competitive ELISA, Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.

Target products collectionGo to Epilepsy diagnostics products collection>>


Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-SMT-202-Ag01BSA-Nitrazepam, Clonazepam(CZP)$756.00
GMP-SMT-202-Ag02OVA-Nitrazepam, Clonazepam(CZP)$756.00
GMP-SMT-202-Ab01Anti-human Nitrazepam, Clonazepam(CZP) mouse monoclonal antibody (mAb)$1953.00
GMP-SMT-202-Ab02Anti-human Nitrazepam, Clonazepam(CZP) human monoclonal antibody (mAb)$1953.00

Size: 1mg | 10mg | 100mg



Product Description

BSA-Nitrazepam, Clonazepam(CZP)

Cat No.GMP-SMT-202-Ag01
Product NameBSA-Nitrazepam, Clonazepam(CZP)
TargetNitrazepam, Clonazepam(CZP)
Expression platformSynthetic
Bioactivity validationNitrazepam, Clonazepam(CZP) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CZP level test of Epilepsy (anxiety, seizures, muscle spasms) and related syndrome evaluation
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates BSA-Nitrazepam, Clonazepam(CZP) / OVA-Nitrazepam, Clonazepam(CZP) is Synthetic.
PurityHigh (TBD)
ApplicationCompetitive immunoassay validation (Competitive ELISA), ELISA, Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

OVA-Nitrazepam, Clonazepam(CZP)

Cat No.GMP-SMT-202-Ag02
Product NameOVA-Nitrazepam, Clonazepam(CZP)
TargetNitrazepam, Clonazepam(CZP)
Expression platformSynthetic
Bioactivity validationNitrazepam, Clonazepam(CZP) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CZP level test of Epilepsy (anxiety, seizures, muscle spasms) and related syndrome evaluation
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates BSA-Nitrazepam, Clonazepam(CZP) / OVA-Nitrazepam, Clonazepam(CZP) is Synthetic.
PurityHigh (TBD)
ApplicationCompetitive immunoassay validation (Competitive ELISA), ELISA, Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Anti-human Nitrazepam, Clonazepam(CZP) mouse monoclonal antibody (mAb)

Cat No.GMP-SMT-202-Ab01
Product NameAnti-human Nitrazepam, Clonazepam(CZP) mouse monoclonal antibody (mAb)
TargetNitrazepam, Clonazepam(CZP)
Expression platformhybridoma
IsotypesMouse IgG
Bioactivity validationNitrazepam, Clonazepam(CZP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Nitrazepam, Clonazepam(CZP) antibodies in CZP level test of Epilepsy (anxiety, seizures, muscle spasms) and related syndrome evaluation.
TagmFc
Products descriptionAnti-human Nitrazepam, Clonazepam(CZP) mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by hybridoma technology.
PurityHigh (TBD)
ApplicationCompetitive immunoassay validation (Competitive ELISA), ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Anti-human Nitrazepam, Clonazepam(CZP) human monoclonal antibody (mAb)

Cat No.GMP-SMT-202-Ab02
Product NameAnti-human Nitrazepam, Clonazepam(CZP) human monoclonal antibody (mAb)
TargetNitrazepam, Clonazepam(CZP)
Expression platformhybridoma
IsotypesHuman IgG1
Bioactivity validationNitrazepam, Clonazepam(CZP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Nitrazepam, Clonazepam(CZP) antibodies in CZP level test of Epilepsy (anxiety, seizures, muscle spasms) and related syndrome evaluation.
TaghFc
Products descriptionAnti-human Nitrazepam, Clonazepam(CZP) mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO.
PurityPurity: ≥95% (SDS-PAGE)
ApplicationCompetitive immunoassay validation (Competitive ELISA), ELISA, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
FormulationSupplied as a 0.2 μM filtered solution of PBS, PH7.4.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker information


    1. **Understanding Nitrazepam and Clonazepam in the Context of In Vitro Diagnosis (IVD)**

       Nitrazepam and Clonazepam, both belonging to the benzodiazepine class of compounds, play significant roles in the fields of neurology and psychiatry. These small molecules have distinct therapeutic applications and are the subject of great interest in in vitro diagnosis (IVD) due to their widespread clinical use.

       **Nitrazepam** is primarily recognized as a sedative-hypnotic agent, commonly prescribed to manage sleep disorders and anxiety. Its mechanism of action involves enhancing the inhibitory neurotransmitter GABA's effects in the brain, resulting in relaxation and sedation. In the context of IVD, Nitrazepam becomes a crucial target for diagnostic assays designed to measure and monitor its levels in biological specimens.

       **Clonazepam**, another benzodiazepine, is distinguished for its role in treating epilepsy, panic disorders, and various anxiety conditions. It exerts its pharmacological effects by modulating GABA receptors, reducing neuronal excitability, and providing anticonvulsant and anxiolytic effects. Similar to Nitrazepam, Clonazepam is a subject of interest in IVD due to its clinical significance.

       Our biopharmaceutical company recognizes the importance of these small molecules in medical practice and specializes in providing anti-Nitrazepam and anti-Clonazepam antibodies, as well as small molecules competitive antigens. This specialized range includes Carrier-coupled antigens, immunogens, hapten-carrier conjugates, BSA-conjugated, and OVA-conjugated forms, meticulously designed to support the development of diagnostic assays tailored for the precise quantification of Nitrazepam and Clonazepam levels in biological matrices, such as blood and urine.

       **The Role of IVD in Nitrazepam and Clonazepam Detection:**

       In vitro diagnosis (IVD) is a critical discipline that employs laboratory-based techniques to analyze biological samples for the detection, diagnosis, and monitoring of various medical conditions. In the case of Nitrazepam and Clonazepam, IVD plays an essential role by providing accurate and sensitive methods for measuring these compounds. This has several practical applications:

       - **Therapeutic Drug Monitoring (TDM):** Patients undergoing Nitrazepam or Clonazepam therapy require precise dosing to achieve therapeutic benefits while minimizing side effects. IVD assays ensure that healthcare providers can tailor treatment regimens to individual patient needs.

       - **Toxicity Prevention:** Both Nitrazepam and Clonazepam have a narrow therapeutic range, and overdosing can lead to severe adverse effects, including respiratory depression. IVD tests offer the ability to detect and prevent potential overdose situations, ensuring patient safety.

       - **Treatment Optimization:** Patients with epilepsy, panic disorders, or anxiety conditions rely on the efficacy of Nitrazepam and Clonazepam. Accurate measurement allows for treatment adjustments to optimize therapeutic outcomes and patient well-being.

       - **Compliance Assessment:** These medications, particularly when prescribed for extended periods, carry a risk of dependence or misuse. Monitoring Nitrazepam and Clonazepam levels helps healthcare providers assess patient adherence and identify potential issues with medication misuse.

       - **Pharmaceutical Research:** In the realm of pharmaceutical research and development, understanding the pharmacokinetics and metabolism of Nitrazepam and Clonazepam is essential. IVD assays for these compounds are crucial for evaluating drug safety profiles, conducting efficacy studies, and optimizing treatment protocols.

    2. **The Imperative for Nitrazepam and Clonazepam Measurement**

       The measurement of Nitrazepam and Clonazepam levels is paramount for several compelling reasons, spanning both clinical and research domains:

       a. **Therapeutic Oversight (Clinical Application):** Patients undergoing Nitrazepam or Clonazepam therapy necessitate vigilant monitoring to ensure accurate dosing tailored to their specific clinical conditions. Accurate measurement empowers healthcare professionals to fine-tune treatment regimens, optimizing therapeutic efficacy and patient well-being.

       b. **Toxicity Mitigation (Clinical Application):** Nitrazepam and Clonazepam possess potent pharmacological properties with a narrow therapeutic range. Measurement capabilities aid in the timely identification and prevention of potential overdose scenarios, averting severe adverse consequences and ensuring patient safety.

       c. **Treatment Optimization (Clinical Application):** Patients grappling with epilepsy, panic disorders, or anxiety conditions rely on the efficacy of Nitrazepam and Clonazepam. Precise measurement enables healthcare providers to make treatment adjustments, ensuring optimal symptom management and improved patient outcomes.

       d. **Compliance Evaluation (Clinical Application):** Given the potential for dependence, especially in the case of extended use, monitoring Nitrazepam and Clonazepam levels facilitates healthcare providers in assessing patient adherence and the likelihood of medication misuse, enabling early intervention when necessary.

       e. **Research Advancements (Research Application):** Within the pharmaceutical research domain, comprehending the pharmacokinetics and metabolic pathways of Nitrazepam and Clonazepam is pivotal for drug development and safety evaluations. Dependable IVD assays for these compounds constitute essential tools in advancing pharmaceutical research, optimizing treatment protocols, and ultimately enhancing patient care.

       In summary, the measurement of Nitrazepam and Clonazepam emerges as a fundamental component in in vitro diagnosis (IVD). It ensures the safe and efficacious utilization of these medications, bolsters various clinical objectives, and underpins progress in neurology and psychiatry research. Our specialized product portfolio is instrumental in facilitating precise and sensitive Nitrazepam and Clonazepam testing, fostering enhanced patient care and scientific exploration in these specialized medical domains. As the field of IVD continues to evolve, our commitment to providing innovative solutions for Nitrazepam and Clonazepam measurement remains unwavering, contributing to improved patient outcomes and advancements in pharmaceutical research.



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