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Description of Small molecules (Chemicals, Antibiotics,Mycotoxins,Hormones,Drugs of Abuse, etc.)

Metronidazole is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities. Although its mechanism of action is not fully elucidated, un-ionized metronidazole is readily taken up by obligate anaerobic organisms and is subsequently reduced by low-redox potential electron-transport proteins to an active, intermediate product. Reduced metronidazole causes DNA strand breaks, thereby inhibiting DNA synthesis and bacterial cell growth.

Metronidazole is a member of the class of imidazoles substituted at C-1, -2 and -5 with 2-hydroxyethyl, nitro and methyl groups respectively. It has activity against anaerobic bacteria and protozoa, and has a radiosensitising effect on hypoxic tumour cells. It may be given by mouth in tablets, or as the benzoate in an oral suspension. The hydrochloride salt can be used in intravenous infusions. Metronidazole is a prodrug and is selective for anaerobic bacteria due to their ability to intracellularly reduce the nitro group of metronidazole to give nitroso-containing intermediates. These can covalently bind to DNA, disrupting its helical structure, inducing DNA strand breaks and inhibiting bacterial nucleic acid synthesis, ultimately resulting in bacterial cell death. It has a role as an antitrichomonal drug, a prodrug, an antibacterial drug, an antimicrobial agent, an antiparasitic agent, a xenobiotic, an environmental contaminant and a radiosensitizing agent. It is a member of imidazoles, a C-nitro compound and a primary alcohol. It is a conjugate base of a metronidazole(1+).

Metronidazole is a nitroimidazole derivative bactericidal agent widely used in the treatment of many anaerobic and certain protozoan and parasitic infections. Metronidazole has been linked to rare instances of acute, clinically apparent liver injury.

Order informatioin


Delivery impact due to the Coronavirus Outbreak

With the COVID-19 outbreak in the world, many flights have been cancelled. In order for the customer to receive the goods properly, we use the FedEx Customized Freight (FCF) of Fedex which demands a higher fee. If the delivery fee is more expensive in your area, we will contact you by mail.

Catalog No. Description Price(In USD) Qty (Quantity) Sum(In USD)
GMP-SMT-33-1 1. BSA-Metronidazole; Size:1mg
2. Anti-Metronidazole mouse monoclonal antibody; Size:1mg
1365
GMP-SMT-33-1 1. BSA-Metronidazole; Size:10mg
2. Anti-Metronidazole mouse monoclonal antibody; Size:10mg
9555
GMP-SMT-33-1 1. BSA-Metronidazole; Size:100mg
2. Anti-Metronidazole mouse monoclonal antibody; Size:100mg
66885
GMP-SMT-33-2 1. OVA-Metronidazole; Size:1mg
2. Anti-Metronidazole mouse monoclonal antibody; Size:1mg
1365
GMP-SMT-33-2 1. OVA-Metronidazole; Size:10mg
2. Anti-Metronidazole mouse monoclonal antibody; Size:10mg
9555
GMP-SMT-33-2 1. OVA-Metronidazole; Size:100mg
2. Anti-Metronidazole mouse monoclonal antibody; Size:100mg
66885
GMP-SMT-33-Ab-1 Anti-Metronidazole mouse monoclonal antibody; Size:1mg 1043
GMP-SMT-33-Ab-1 Anti-Metronidazole mouse monoclonal antibody; Size:10mg 7301
GMP-SMT-33-Ab-1 Anti-Metronidazole mouse monoclonal antibody; Size:100mg 51107
GMP-SMT-33-Ag-1 BSA-Metronidazole; Size:1mg 756
GMP-SMT-33-Ag-1 BSA-Metronidazole; Size:10mg 5292
GMP-SMT-33-Ag-1 BSA-Metronidazole; Size:100mg 37044
GMP-SMT-33-Ag-2 OVA-Metronidazole; Size:1mg 756
GMP-SMT-33-Ag-2 OVA-Metronidazole; Size:10mg 5292
GMP-SMT-33-Ag-2 OVA-Metronidazole; Size:100mg 37044
GMP-SMT-33 ≥100mg Inquiry
Shipping Cost: 760.00
Total:



Description


BSA-Metronidazole

Cat No. GMP-SMT-33-Ag-1
Bioactivity validation Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products description Competitive immunoassay-validated hapten-carrier conjugates [BSA-Metronidazole)]with anti-Hapten antibody. The hapten hapten-carrier conjugates [BSA-Metronidazole)] had been validated with our anti-Hapten antibody[Anti-Metronidazole mouse monoclonal antibody] via competitive ELISA test.
Application ELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


OVA-Metronidazole

Cat No. GMP-SMT-33-Ag-2
Bioactivity validation Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products description Competitive immunoassay-validated hapten-carrier conjugates [ OVA-Metronidazole)] with anti-Hapten antibody. The hapten hapten-carrier conjugates[ OVA-Metronidazole)] had been validated with our anti-Hapten antibody[Anti-Metronidazole mouse monoclonal antibody] via competitive ELISA test.
Application ELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Metronidazole mouse monoclonal antibody

Cat No. GMP-SMT-33-Ab-1
Host of Antibody Mouse IgG
Bioactivity validation Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb) 0.6-1
Products description The anti-Hapten antibody against hapten [Metronidazole)] had beenvalidated with our hapten hapten-carrier conjugates [BSA-Metronidazole)] via competitive ELISA test.
Application ELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.