Quinolones antibody/antigen (BSA/OVA/KLH conjugated hapten)

anti-Quinolones antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-SMT-61-11. BSA-Quinolones
2. Anti-Quinolones mouse monoclonal antibody
$2709.00
GMP-SMT-61-21. OVA-Quinolones
2. Anti-Quinolones mouse monoclonal antibody
$2709.00
GMP-SMT-61-31. BSA-Quinolones
2. Anti-Quinolones human monoclonal antibody
$2709.00
GMP-SMT-61-41. OVA-Quinolones
2. Anti-Quinolones human monoclonal antibody
$2709.00
GMP-SMT-61-Ag-1BSA-Quinolones$756.00
GMP-SMT-61-Ag-2OVA-Quinolones$756.00
GMP-SMT-61-Ab-1Anti-Quinolones mouse monoclonal antibody$1953.00
GMP-SMT-61-Ab-2Anti-Quinolones human monoclonal antibody$1953.00

Size: 1mg | 10mg | 100mg



Product Description


BSA-Quinolones

Cat No.GMP-SMT-61-Ag-1
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates BSA-Quinolones with anti-Hapten antibody. The hapten hapten-carrier conjugates BSA-Quinolones had been validated with our anti-Hapten antibody Anti-Quinolones mouse monoclonal antibody via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


OVA-Quinolones

Cat No.GMP-SMT-61-Ag-2
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products descriptionCompetitive immunoassay-validated hapten-carrier conjugates OVA-Quinolones with anti-Hapten antibody. The hapten hapten-carrier conjugates OVA-Quinolones had been validated with our anti-Hapten antibody Anti-Quinolones mouse monoclonal antibody via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Quinolones mouse monoclonal antibody

Cat No.GMP-SMT-61-Ab-1
Host of AntibodyMouse IgG
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)0.50
Products descriptionThe anti-Hapten antibody against hapten Quinolones had been validated with our hapten hapten-carrier conjugates BSA-Quinolones via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Anti-Quinolones human monoclonal antibody

Cat No.GMP-SMT-61-Ab-2
Host of AntibodyHuman IgG1
Bioactivity validationCompetitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)0.50
Products descriptionThe anti-Hapten antibody against hapten Quinolones had been validated with our hapten hapten-carrier conjugates BSA-Quinolones via competitive ELISA test.
ApplicationELISA tests and other immunoassays;
Lateral flow immunoassay (LFIA);
LTIA
Immunonephelometry
Time-resolved Fluorescence Immunoassay (TRFIA)
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study


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    Biomarker Information


    1. Quinolones in Veterinary Drug Residues and Additives

    1.1 Veterinary Drug Residues

    Quinolones are a class of synthetic antibiotics known for their versatility in combating bacterial infections. They are integral to the fields of human and veterinary medicine. In the context of veterinary drug residues, quinolones play a pivotal role, and their impact is far-reaching.

    Veterinary drug residues refer to the remnants of pharmaceuticals, including quinolones, that persist in animal-derived products such as meat, milk, and eggs after the administration of these antibiotics to animals. The use of quinolones in veterinary medicine is common, as they are effective against a wide range of bacterial pathogens. However, the presence of quinolone residues in animal products raises several critical concerns.

    1.1.1 Food Safety and Consumer Health

    Excessive quinolone residues in animal-derived products can pose a significant risk to consumer health. When humans consume meat, milk, or eggs containing elevated levels of quinolones, there is the potential for adverse health effects. These may range from allergic reactions to more severe consequences, including the development of antibiotic resistance in human pathogens.

    1.1.2 Regulatory Compliance

    To ensure the safety of food products, regulatory agencies in many countries have established maximum residue limits (MRLs) for quinolones and other veterinary drug residues. These MRLs define the acceptable concentration of quinolones in animal-derived products. Companies in the biopharmaceutical sector must provide accurate measurement solutions to help food producers comply with these regulatory standards. Non-compliance can have severe consequences, including product recalls, fines, and damage to a company's reputation.

    1.2 Veterinary Additives

    In addition to their use in treating bacterial infections in animals, quinolones are also employed as additives in animal feed. These additives serve a dual purpose: promoting growth in livestock and preventing bacterial infections in the animals.

    1.2.1 Growth Promotion

    Quinolones, when used as growth promoters, enhance the weight gain and overall development of livestock. By improving feed conversion efficiency, these antibiotics have become a valuable tool in modern animal husbandry. However, it is essential to ensure that quinolones are used within approved dosage limits to prevent overexposure and potential health risks to the animals.

    1.2.2 Health and Safety

    Beyond growth promotion, quinolones serve a vital role in protecting animal health. In crowded and often stressful farming environments, animals are susceptible to bacterial infections. Quinolone additives in animal feed help prevent and control these infections, reducing the need for therapeutic antibiotics. However, as with any pharmaceutical used in agriculture, careful measurement and control of quinolone levels in animal feed are necessary to safeguard animal well-being and food safety.

    2. The Significance of Measuring Quinolones

    2.1 Food Safety Assurance

    The precise measurement of quinolones is paramount to guaranteeing the safety of animal-derived food products. This assurance hinges on several critical factors.

    First and foremost, it allows for the monitoring and control of quinolone levels in meat, milk, eggs, and other food products. By adhering to established MRLs, the presence of quinolones in these products can be kept within safe limits. This ensures that consumers are not exposed to excessive antibiotic residues, reducing the risk of adverse health effects and the development of antibiotic-resistant bacteria.

    Accurate measurement also aids in identifying and mitigating potential food safety risks. It enables the timely detection of any deviations from established safety standards, allowing for immediate corrective actions. This proactive approach is essential in preventing foodborne illnesses and maintaining consumer trust in the safety of animal-derived products.

    2.2 Antibiotic Resistance Mitigation

    The overuse and misuse of antibiotics, including quinolones, in both human and veterinary medicine have contributed to the emergence of antibiotic-resistant bacteria. Measuring quinolones is a critical component of antibiotic stewardship efforts.

    Quantitative analysis of quinolones helps in tracking their usage in animals and assessing the risk of antibiotic resistance development. This information is invaluable for public health efforts, as antibiotic resistance poses a significant threat to human and animal health. By measuring quinolones, biopharmaceutical companies can contribute to the responsible use of antibiotics and the mitigation of antibiotic resistance.

    2.3 Regulatory Compliance

    Stringent regulatory standards and MRLs exist in many countries to ensure the safety of animal-derived food products. Accurate measurement solutions are indispensable for achieving and maintaining regulatory compliance.

    Failure to comply with these standards can result in significant consequences for both biopharmaceutical companies and food producers. These consequences may include product recalls, fines, and reputational damage. By providing reliable measurement tools and solutions, biopharmaceutical companies empower the food industry to meet regulatory requirements and avoid non-compliance.

    In conclusion, the measurement of quinolones is pivotal for upholding public health, fostering responsible antibiotic use, and ensuring alignment with regulatory mandates in the veterinary and food production industries. It is an essential component of both food safety and antibiotic resistance mitigation efforts, offering a comprehensive approach to safeguarding consumer health and the sustainability of the food supply chain.



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