Diagnostic anti-Babesia caballi P50 antibodies pairs and antigen for animal health (animal Dog/Canine, Bovines/Cattle, Equine/Horse infectious disease babesiosis) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Genemedi produces core animal health diagnostic ingredients-validated anti-Babesia caballi P50 antibodies pairs and antigens for rapid test kit of animal Dog/Canine, Bovines/Cattle, Equine/Horse infectious disease with babesiosis to evaluate the  animal health of Multiple species (Pet, Ruminants, Equine/Horse).

The paired antibodies are both monoclonal antibodies (mab).

All the antibodies and antigens of  animal disease test are suitable for in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT. The antibody can act as a capture antibody and detection antibody. Antigens are validated as positive control materials.

Babesia is a protozoan parasite found to infect vertebrate animals, mostly livestock mammals and birds, but also occasionally humans. Common names of the disease that Babesia microti causes are Texas cattle fever, redwater fever, tick fever, and Nantucket fever.Canine babesiosis is a hemoprotozoan infection typically caused by Babesia canis or Babesia gibsoni. Babesia gibsoni is a tickborne protozoal blood parasite that causes hemolytic anemia, thrombocytopenia, lethargy, and splenomegaly. quine babesiosis in India has always been a severe and life-threatening disease attributed to infection with Theileria equi and Babesia caballi. These organisms are not host-specific, as both T. equi and B. caballi are reported in dogs. Likewise, Babesia canis canis and Babesia canis rossi, the common causative agents in canines, have also been identified in horses. However, no molecular evidence of Babesia gibsoni has been reported in horses in India. A 5-year-old Thoroughbred gelding residing in Bengaluru showed signs of recurrent intermittent fever, inappetence, poor performance, anaemia and depression. A regular complete blood count and biochemical profile were done, however, the results were unresponsive to treatment interventions. The blood sample was submitted for screening equine haemoprotozoans using polymerase chain reaction. The current blood sample was screened for haemoprotozoans. The sample was positive for B. gibsoni and was confirmed by sequencing. Basic Local Alignment Search Tool (BLAST) search against GenBank revealed the highest similarity (95.17%, Accession No. MN385430.1) with B. gibsoni 18s rRNA partial sequence.

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