Equine/Horse morbillivirus Matrix and fusion proteins antibody and antigen (recombinant protein)

Diagnostic anti-Equine/Horse morbillivirus Matrix and fusion proteins antibodies pairs and antigen for animal health (animal Equine/Horse infectious disease Equine/Horse morbillivirus pneumonia) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P148-Tg001-Ag01 Recombinant Equine/Horse morbillivirus Matrix and fusion proteins protein $3090.00
GMP-VT-P148-Tg001-Ab01 Anti-Equine/Horse morbillivirus Matrix and fusion proteins mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P148-Tg001-Ab02 Anti-Equine/Horse morbillivirus Matrix and fusion proteins mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P148-Tg001-Ab03 Anti-Equine/Horse morbillivirus Matrix and fusion proteins human monoclonal antibody (mAb) $3090.00
GMP-VT-P148-Tg001-Ab04 Anti-Equine/Horse morbillivirus Matrix and fusion proteins human monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P148-Tg001-Ag01
Product Name Recombinant Equine/Horse morbillivirus Matrix and fusion proteins protein
Pathogen Equine/Horse morbillivirus
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Equine/Horse morbillivirus Matrix and fusion proteins antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Equine/Horse morbillivirus level test of animal Equine/Horse infectious disease with Equine/Horse morbillivirus pneumonia.
Tag His
Product description Recombinant Equine/Horse morbillivirus Matrix and fusion proteins proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P148-Tg001-Ab01,GMP-VT-P148-Tg001-Ab02
Pathogen Equine/Horse morbillivirus
Product Name Anti-Equine/Horse morbillivirus Matrix and fusion proteins mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Equine/Horse morbillivirus Matrix and fusion proteins antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine/Horse morbillivirus antibodies in Equine/Horse morbillivirus level test of animal Equine/Horse infectious disease with Equine/Horse morbillivirus pneumonia.
Product description Anti-Equine/Horse morbillivirus Matrix and fusion proteins mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine/Horse morbillivirus antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P148-Tg001-Ab03,GMP-VT-P148-Tg001-Ab04
Pathogen Equine/Horse morbillivirus
Product Name Anti-Equine/Horse morbillivirus Matrix and fusion proteins human monoclonal antibody (mAb)
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Recombinant Equine/Horse morbillivirus Matrix and fusion proteins antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Equine/Horse morbillivirus antibodies in Equine/Horse morbillivirus level test of animal Equine/Horse infectious disease with Equine/Horse morbillivirus pneumonia.
Product description Anti-Equine/Horse morbillivirus Matrix and fusion proteins mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




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    Pathogen Information


    Equine Morbillivirus: A Hypothetical Pathogen for Equine Health

    Introduction:

    Equine Morbillivirus, a theoretical member of the Morbillivirus genus within the Paramyxoviridae family, is a construct designed to simulate the characteristics of a virus that could specifically affect equine hosts, particularly horses (Equus ferus caballus). While this pathogen is hypothetical, a detailed understanding of its theoretical properties may offer insights into the potential challenges and diagnostic strategies in the realm of equine virology.

    Pathogen Classification:

    Theoretical Pathogen Classification:

    Type: Virus

    Family: Paramyxoviridae

    Genus: Morbillivirus

    Pathogen Structure:

    Equine Morbillivirus, like other morbilliviruses, is characterized by a single-stranded, negative-sense RNA genome. The viral genome comprises several critical genes and proteins:

    Nucleoprotein (N): The N gene encodes the nucleoprotein, essential for encapsidating the viral RNA.

    Phosphoprotein (P): The P gene encodes the phosphoprotein, which plays a crucial role in viral replication and transcription.

    Matrix protein (M): Encoded by the M gene, this protein contributes to the structure of the virus particle and its assembly.

    Fusion protein (F): The F gene encodes the fusion protein, responsible for mediating viral entry into host cells.

    Hemagglutinin protein (H): Encoded by the H gene, this protein is pivotal in viral attachment to host cell receptors, facilitating infection.

    Large protein (L): The L gene encodes the large protein, responsible for the RNA-dependent RNA polymerase activity, essential for viral replication.

    Hosts and Associated Diseases:

    Equine Morbillivirus, in our hypothetical scenario, primarily infects horses. The disease caused by this pathogen is referred to as "Equine Morbillivirus Disease." The hypothetical clinical manifestations of this disease might include respiratory symptoms, fever, and other systemic signs, similar to other morbillivirus infections in their respective hosts.

    Diagnostic Methods:

    In the event of a suspected Equine Morbillivirus infection, veterinarians and researchers would employ various diagnostic methods to identify and confirm the presence of the virus. These methods encompass:

    Polymerase Chain Reaction (PCR): PCR is a fundamental tool for the detection of viral nucleic acids. Specific primers designed for Equine Morbillivirus genes, such as H or N, are utilized to amplify viral RNA for identification.

    Enzyme-Linked Immunosorbent Assay (ELISA): ELISA tests employ antibodies designed to recognize Equine Morbillivirus proteins, particularly H and F. By binding to these proteins, the presence of the virus can be detected.

    Virus Isolation: This technique involves attempts to cultivate and isolate the virus within suitable cell lines. It not only confirms the virus's presence but also provides a sample for further characterization and study.

    Serological Tests: Detecting Equine Morbillivirus-specific antibodies in the host's immune response is another crucial diagnostic approach. It indicates exposure to the virus and potential immunity.

    Immunohistochemistry: In cases where post-mortem tissue samples are available, immunohistochemistry allows for the identification of viral antigens within tissues. This can provide insights into the pathogenesis of the disease.

    Genes/Proteins Targeted in Diagnostic Methods:

    The diagnostic methods mentioned above are tailored to target specific Equine Morbillivirus genes and proteins:

    Hemagglutinin (H): This protein is a key target in both PCR and ELISA methods due to its essential role in viral attachment and membrane fusion.

    Nucleoprotein (N): The N gene and protein are often the focus of PCR-based diagnostics, allowing for the detection of the viral genome.

    Fusion (F): The F protein is targeted in ELISA tests to confirm the presence of Equine Morbillivirus.

    In conclusion, while Equine Morbillivirus is a hypothetical pathogen, understanding its theoretical properties, diagnostic approaches, and potential impact on equine health can serve as a valuable exercise for researchers and veterinarians in preparing for real-world challenges in equine virology. It underscores the importance of robust diagnostic techniques in managing and controlling potential viral threats to horse populations. Please note that this information is purely hypothetical and should not be considered as representative of any real-world pathogen. For accurate and updated information on actual pathogens, consult authoritative sources and scientific literature.



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