Infectious Bronchitis Virus - Variant Massachusetts S1 antibody and antigen (recombinant protein)

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Diagnostic anti-Infectious Bronchitis Virus - Variant Massachusetts S1 antibodies pairs and antigen for animal health (animal Avian/Bird/Poultry infectious disease respiratory disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P154-Tg001-Ag01	Recombinant Infectious Bronchitis Virus - Variant Massachusetts S1 protein	$3090.00
GMP-VT-P154-Tg001-Ab01	Anti-Infectious Bronchitis Virus - Variant Massachusetts S1 mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P154-Tg001-Ab02	Anti-Infectious Bronchitis Virus - Variant Massachusetts S1 mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P154-Tg001-Ab03	Anti-Infectious Bronchitis Virus - Variant Massachusetts S1 human monoclonal antibody (mAb)	$3090.00
GMP-VT-P154-Tg001-Ab04	Anti-Infectious Bronchitis Virus - Variant Massachusetts S1 human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P154-Tg001-Ag01
Product Name	Recombinant Infectious Bronchitis Virus - Variant Massachusetts S1 protein
Pathogen	Infectious Bronchitis Virus - Variant Massachusetts
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Infectious Bronchitis Virus - Variant Massachusetts S1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Infectious Bronchitis Virus - Variant Massachusetts level test of animal Avian/Bird/Poultry infectious disease with respiratory disease.
Tag	His
Product description	Recombinant Infectious Bronchitis Virus - Variant Massachusetts S1 proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P154-Tg001-Ab01,GMP-VT-P154-Tg001-Ab02
Pathogen	Infectious Bronchitis Virus - Variant Massachusetts
Product Name	Anti-Infectious Bronchitis Virus - Variant Massachusetts S1 mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Infectious Bronchitis Virus - Variant Massachusetts S1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Infectious Bronchitis Virus - Variant Massachusetts antibodies in Infectious Bronchitis Virus - Variant Massachusetts level test of animal Avian/Bird/Poultry infectious disease with respiratory disease.
Product description	Anti-Infectious Bronchitis Virus - Variant Massachusetts S1 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Infectious Bronchitis Virus - Variant Massachusetts antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P154-Tg001-Ab03,GMP-VT-P154-Tg001-Ab04
Pathogen	Infectious Bronchitis Virus - Variant Massachusetts
Product Name	Anti-Infectious Bronchitis Virus - Variant Massachusetts S1 human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Infectious Bronchitis Virus - Variant Massachusetts S1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Infectious Bronchitis Virus - Variant Massachusetts antibodies in Infectious Bronchitis Virus - Variant Massachusetts level test of animal Avian/Bird/Poultry infectious disease with respiratory disease.
Product description	Anti-Infectious Bronchitis Virus - Variant Massachusetts S1 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

IBV-Mass is a highly infectious avian virus that primarily infects chickens, causing the respiratory disease known as infectious bronchitis. This virus belongs to the family Coronaviridae, which also includes notable human pathogens such as Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and Middle East Respiratory Syndrome Coronavirus (MERS-CoV). IBV-Mass is a positive-sense, single-stranded RNA virus with an envelope and a genome size of approximately 27-32 kilobases.

The major structural proteins of IBV-Mass are the spike (S) glycoprotein and nucleocapsid (N) protein. The S protein plays a crucial role in viral attachment and entry into host cells by binding to specific receptors on the surface of host cells, while the N protein mediates viral genome replication and packaging. The spike protein of IBV-Mass has been reported to be involved in tissue tropism and host range, with different spike protein sequences conferring differences in receptor binding and pathogenicity.

The incubation period of IBV-Mass ranges from 18 to 48 hours, and clinical signs usually appear 24 to 72 hours after infection. The main symptoms include respiratory signs such as coughing, sneezing, and nasal discharge, as well as depression, ruffled feathers, and decreased feed and water intake. Additionally, IBV-Mass infections can lead to decreased egg production in laying hens, as well as poor egg quality and hatchability.

To diagnose IBV-Mass infections, various methods can be employed, including virus isolation, serological assays, and molecular techniques such as reverse transcription polymerase chain reaction (RT-PCR). Virus isolation involves culturing the virus from infected tissues or swabs and observing characteristic cytopathic effects (CPE) in cell culture. Serological assays detect antibodies against IBV-Mass in serum, plasma, or egg yolk samples using methods such as enzyme-linked immunosorbent assay (ELISA) or hemagglutination inhibition (HI). Molecular techniques such as RT-PCR are highly sensitive and specific for detecting IBV-Mass infections, targeting conserved regions of the viral genome such as the S and N genes or the 3' untranslated region (UTR). These methods can be used for rapid diagnosis, identification of viral strains, and monitoring of disease outbreaks.

Other advanced diagnostic techniques may be employed to detect and characterize IBV-Mass infections in atypical situations, such as cases with mixed infections or those that fail to yield conclusive results using traditional methods. For example, next-generation sequencing (NGS) and metagenomic analysis can be used to identify known and novel viruses in complex samples, including respiratory and fecal samples from infected birds. These methods can also provide valuable insights into the genetic diversity, evolution, and pathogenic potential of IBV-Mass and other viral pathogens.

In summary, IBV-Mass is a highly infectious avian virus that causes respiratory disease in chickens, leading to significant economic losses in the poultry industry worldwide. The virus possesses unique structural and functional features that contribute to its tissue tropism, host range, and pathogenicity. Various methods can be employed to diagnose and monitor IBV-Mass infections, including virus isolation, serological assays, and molecular techniques such as RT-PCR and NGS. The development and implementation of effective preventive and control measures against IBV-Mass are essential to minimize its impact on poultry health and production.

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