Goose hemorrhagic Polyomavirus VP1 antibody and antigen (recombinant protein)

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Diagnostic anti-Goose hemorrhagic Polyomavirus VP1 antibodies pairs and antigen for animal health (animal Goose infectious disease Hemorrhagic Nephritis Enteritis of Geese) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P210-Tg001-Ag01	Recombinant Goose hemorrhagic Polyomavirus VP1 protein	$3090.00
GMP-VT-P210-Tg001-Ab01	Anti-Goose hemorrhagic Polyomavirus VP1 mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P210-Tg001-Ab02	Anti-Goose hemorrhagic Polyomavirus VP1 mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P210-Tg001-Ab03	Anti-Goose hemorrhagic Polyomavirus VP1 human monoclonal antibody (mAb)	$3090.00
GMP-VT-P210-Tg001-Ab04	Anti-Goose hemorrhagic Polyomavirus VP1 human monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P210-Tg001-Ag01
Product Name	Recombinant Goose hemorrhagic Polyomavirus VP1 protein
Pathogen	Goose hemorrhagic Polyomavirus
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Goose hemorrhagic Polyomavirus VP1 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Goose hemorrhagic Polyomavirus level test of animal Goose infectious disease with Hemorrhagic Nephritis Enteritis of Geese.
Tag	His
Product description	Recombinant Goose hemorrhagic Polyomavirus VP1 proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P210-Tg001-Ab01,GMP-VT-P210-Tg001-Ab02
Pathogen	Goose hemorrhagic Polyomavirus
Product Name	Anti-Goose hemorrhagic Polyomavirus VP1 mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Goose hemorrhagic Polyomavirus VP1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Goose hemorrhagic Polyomavirus antibodies in Goose hemorrhagic Polyomavirus level test of animal Goose infectious disease with Hemorrhagic Nephritis Enteritis of Geese.
Product description	Anti-Goose hemorrhagic Polyomavirus VP1 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Goose hemorrhagic Polyomavirus antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P210-Tg001-Ab03,GMP-VT-P210-Tg001-Ab04
Pathogen	Goose hemorrhagic Polyomavirus
Product Name	Anti-Goose hemorrhagic Polyomavirus VP1 human monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Recombinant Goose hemorrhagic Polyomavirus VP1 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Goose hemorrhagic Polyomavirus antibodies in Goose hemorrhagic Polyomavirus level test of animal Goose infectious disease with Hemorrhagic Nephritis Enteritis of Geese.
Product description	Anti-Goose hemorrhagic Polyomavirus VP1 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from sterile PBS, PH 7.4
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen Information

GHPV is a member of the family Parvoviridae, which consists of small non-enveloped viruses with a single-stranded DNA genome. Within the Parvoviridae, GHPV belongs to the genus Dependoparvovirus, which is characterized by the ability of its members to replicate in non-dividing cells.

The GHPV genome is about 5.2 kilobases in length and contains a single coding region that encodes for two main proteins: VP1 and VP2. VP1 is the major capsid protein that makes up the outer shell of the virus particle, while VP2 is a minor capsid protein that also plays a role in viral replication.

Transmission of GHPV typically occurs via the fecal-oral route, with the virus being shed in the feces of infected birds. Once ingested, the virus infects and replicates in the epithelial cells lining the gastrointestinal tract and then spreads systemically to other organs via the bloodstream.

Clinical signs of GHPV infection in geese can vary depending on the age and immune status of the bird. In young birds, the disease can be acute and severe, with symptoms such as fever, lethargy, anorexia, diarrhea, and bleeding from multiple sites, including the beak, eyes, and cloaca. Adult geese may develop a milder form of the disease that is characterized by reduced egg production and decreased fertility.

Diagnosis of GHPV infection can be challenging due to the varying severity and nonspecific nature of clinical signs. However, several diagnostic methods are available, including nucleic acid-based techniques such as polymerase chain reaction (PCR), reverse transcription PCR (RT-PCR), and quantitative PCR (qPCR). These methods target the VP1 gene sequence, which is highly conserved among GHPV strains.

Another method for detecting GHPV infection is enzyme-linked immunosorbent assay (ELISA), which detects the presence of antibodies against VP2 protein in infected individuals. ELISA can be useful for serological surveillance and for determining the prevalence of GHPV in a given population.

There is no specific treatment for GHPV infection, and management of affected flocks typically involves supportive care and prevention of secondary bacterial infections. Vaccines have been developed for GHPV, but their efficacy can vary depending on the strain of virus and the age of the bird.

In conclusion, Goose Hemorrhagic Polyomavirus (GHPV) is a DNA virus that primarily infects geese, causing hemorrhagic disease with varying clinical signs depending on the age and immune status of the bird. Diagnosis of GHPV infection can be challenging, but several diagnostic methods are available, including nucleic acid-based techniques and ELISA. Management of GHPV-infected flocks typically involves supportive care and prevention of secondary infections.

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