Spring Viraemia of Carp Virus G protein (3094–4170 bp) antibody and antigen (recombinant protein)

Diagnostic anti-Spring Viraemia of Carp Virus G protein (3094–4170 bp) antibodies pairs and antigen for animal health (animal Carp, Cyprinid, Ictalurid fish infectious disease Spring viraemia of carp) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No. Description US $ Price (per mg)
GMP-VT-P230-Tg001-Ag01 Recombinant Spring Viraemia of Carp Virus G protein (3094–4170 bp) protein $3090.00
GMP-VT-P230-Tg001-Ab01 Anti-Spring Viraemia of Carp Virus G protein (3094–4170 bp) mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P230-Tg001-Ab02 Anti-Spring Viraemia of Carp Virus G protein (3094–4170 bp) mouse monoclonal antibody (mAb) $3090.00
GMP-VT-P230-Tg001-Ab03 Anti-Spring Viraemia of Carp Virus G protein (3094–4170 bp) human monoclonal antibody (mAb) $3090.00
GMP-VT-P230-Tg001-Ab04 Anti-Spring Viraemia of Carp Virus G protein (3094–4170 bp) human monoclonal antibody (mAb) $3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-VT-P230-Tg001-Ag01
Product Name Recombinant Spring Viraemia of Carp Virus G protein (3094–4170 bp) protein
Pathogen Spring Viraemia of Carp Virus
Expression platform E.coli
Isotypes Recombinant Antigen
Bioactivity validation Anti-Spring Viraemia of Carp Virus G protein (3094–4170 bp) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Spring Viraemia of Carp Virus level test of animal Carp, Cyprinid, Ictalurid fish infectious disease with Spring viraemia of carp.
Tag His
Product description Recombinant Spring Viraemia of Carp Virus G protein (3094–4170 bp) proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P230-Tg001-Ab01,GMP-VT-P230-Tg001-Ab02
Pathogen Spring Viraemia of Carp Virus
Product Name Anti-Spring Viraemia of Carp Virus G protein (3094–4170 bp) mouse monoclonal antibody (mAb)
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Recombinant Spring Viraemia of Carp Virus G protein (3094–4170 bp) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Spring Viraemia of Carp Virus antibodies in Spring Viraemia of Carp Virus level test of animal Carp, Cyprinid, Ictalurid fish infectious disease with Spring viraemia of carp.
Product description Anti-Spring Viraemia of Carp Virus G protein (3094–4170 bp) mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Spring Viraemia of Carp Virus antibodies.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. GMP-VT-P230-Tg001-Ab03,GMP-VT-P230-Tg001-Ab04
Pathogen Spring Viraemia of Carp Virus
Product Name Anti-Spring Viraemia of Carp Virus G protein (3094–4170 bp) human monoclonal antibody (mAb)
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Recombinant Spring Viraemia of Carp Virus G protein (3094–4170 bp) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Spring Viraemia of Carp Virus antibodies in Spring Viraemia of Carp Virus level test of animal Carp, Cyprinid, Ictalurid fish infectious disease with Spring viraemia of carp.
Product description Anti-Spring Viraemia of Carp Virus G protein (3094–4170 bp) mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity Purity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation Lyophilized from sterile PBS, PH 7.4
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Data / case study


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    Pathogen Information


    Spring Viraemia of Carp Virus (SVCV) is a viral pathogen that poses a significant threat to the global aquaculture industry. The virus primarily infects cyprinid fish species, such as common carp, rainbow trout, and catfish, causing a range of diseases that can result in high mortality rates and severe economic losses.

    SVCV is a member of the family Rhabdoviridae, a diverse group of RNA viruses that includes a variety of animal and plant pathogens, such as rabies virus and vesicular stomatitis virus. SVCV is classified as a negative-sense single-stranded RNA virus, which means that its genome is complementary to its mRNA and must be copied by the virus's own RNA polymerase to produce viral proteins. The virus has a bullet-shaped structure, with a diameter of approximately 180 nm and a length of 70-180 nm.

    The SVCV genome is encapsulated by the nucleoprotein (N), which is required for viral replication and transcription. The glycoprotein (G) on the surface of the virus is responsible for cell attachment and entry. The G protein has been identified as the major protective antigen of the virus, which induces strong antibody responses in infected fish. The G protein is also highly variable, with several distinct genetic lineages of SVCV identified based on its sequence variation.

    SVCV infects a wide range of freshwater fish species, with cyprinid fishes being particularly susceptible to infection. The virus is transmitted horizontally, usually through water or close contact between infected and susceptible fish. Infection is also possible through vertical transmission from infected parents to their offspring. SVCV is able to replicate in various tissues, including the kidney, spleen, liver, and blood, leading to systemic infection and the characteristic clinical signs of disease.

    The diseases caused by SVCV include Spring Viraemia of Carp Disease (SVC), Infectious Haematopoietic Necrosis (IHN), Viral Haemorrhagic Septicaemia (VHS), and Infectious Pancreatic Necrosis (IPN). SVC is the most common disease caused by SVCV and is characterized by necrosis of the kidney and spleen, leading to haemorrhage and mortality rates of up to 100%. IHN is another serious disease caused by SVCV, which affects the hematopoietic system of fish and can result in high mortality rates. VHS is a viral disease that affects a variety of fish species, including salmonids and cyprinids, and can cause external and internal bleeding. IPN is a severe systemic disease that primarily affects salmonids and is characterized by necrosis of the pancreatic tissue and other organs.

    Early detection and diagnosis of SVCV infection are crucial for effective disease management and prevention of spread. Diagnostic methods for SVCV include nucleic acid-based techniques such as reverse transcription polymerase chain reaction (RT-PCR) and real-time PCR. These methods target the N and G genes of the virus, which enables the rapid and specific detection of the virus in clinical specimens. Other diagnostic methods include enzyme-linked immunosorbent assay (ELISA), virus isolation, and histopathology. These methods provide valuable information on the extent and severity of the infection, and can aid in the development of effective vaccination strategies.

    In recent years, several approaches have been explored for the control and prevention of SVCV infection. These include vaccination with inactivated or attenuated vaccines, administration of antiviral compounds, and implementation of biosecurity measures to prevent the introduction and spread of infection. The development and deployment of effective strategies for the control and prevention of SVCV infection remain a priority for the aquaculture industry, which relies heavily on the health and productivity of its fish stocks.



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