Clostridium perfringens Epsilon antibody and antigen (recombinant protein)

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Product information

Size： 1mg | 10mg | 100mg

Catalog No.	Description	US $ Price (per mg)	First Order Discount	First Order Discount Price
GMP-VT-P260-Tg001-Ag01	Recombinant Clostridium perfringens Epsilon protein	3090
GMP-VT-P260-Tg001-Ab01	Anti-Clostridium perfringens Epsilon mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-VT-P260-Tg001-Ab02	Anti-Clostridium perfringens Epsilon mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-VT-P260-Tg001-Ab03	Anti-Clostridium perfringens Epsilon mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-VT-P260-Tg001-Ab04	Anti-Clostridium perfringens Epsilon mouse monoclonal antibody (mAb)	1953	20%	1562.4

Shipping Costs: $360–$760
Antibodies: $360 Antigens: $760 (Elevated cost due to antigen heterogeneity, post-translational modifications, structural complexity, and specialized handling.)

Product Description

Cat No. of Products	GMP-VT-P260-Tg001-Ag01
Product Name	Recombinant Clostridium perfringens Epsilon protein
Pathogen	Clostridium perfringens
Target/Biomarker	Epsilon
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Clostridium perfringens Epsilon antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Clostridium perfringens level test of animal Cat/Feline, Dog/Canine, Rabbit, Bovines/Cattle, Equine/Horse, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig, Avian/Bird/Poultry with Clostridium perfringens infection.
Tag	His
Products description	Recombinant Clostridium perfringens Epsilon protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-VT-P260-Tg001-Ab01, GMP-VT-P260-Tg001-Ab02, GMP-VT-P260-Tg001-Ab03, GMP-VT-P260-Tg001-Ab04
Product Name	Anti-Clostridium perfringens Epsilon mouse monoclonal antibody (mAb)
Pathogen	Clostridium perfringens
Target/Biomarker	Epsilon
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Clostridium perfringens Epsilon antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Clostridium perfringens antibodies in Clostridium perfringens level test of animal Cat/Feline, Dog/Canine, Rabbit, Bovines/Cattle, Equine/Horse, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig, Avian/Bird/Poultry with Clostridium perfringens infection.
Tag	mFc
Products description	Anti-Clostridium perfringens Epsilon mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

The gram positive anaerobic bacterium Clostridium perfringens belongs to the physiological intestinal flora of many mammals and is facultative pathogenic. Inconvenient endogeneous (other basic diseases, diarrhoea pathogens, antibiotic therapies with massive reduction of intestinal flora etc.) and exogeneous (farming conditions, extreme changes of the food, stress etc.) factors can lead to an increased pathogenicity of C. perfringens. Next to its ability to form extremely infectious and stable spores, the formation of lethal toxins is crucial for its pathogenicity. The classification into the various types (A–E) is only due to the toxin formation. These toxins can cause extremely variable (mild to lethal progression forms) failures of the intestinal water and electrolyte balance in the different species like goat, sheep (e. g. dysenteria of lambs: type B; pulpy kidney disease: type D), cattle (haemorrhagic enteritis: type A–E), foal (haemorrhagic necrotising enteritis: type A & C) and piglet (e. g. serous-catarrhal enteritis: type A, necrotising enteritis: type C). In the dog, especially serotype A occurs, producing 2 main toxins (toxin Alpha [α] and a Clostridia enterotoxin [CPE]), rarer serotype B (toxin Beta [β]). Both C. perfringens and its CPE can be detected also in healthy dog’s feces. The CPE can be detected more often in dogs with diarrhoea compared to healthy dogs. CPE is more frequent in dogs with diarrhoea (haemorrhagic gastroenteritis, acute or chronic diarrhoea, enterotoxaemia) than in healthy dogs. For cats, to date reliable literature data concerning prevalence and clinical relevance are missing. Only by detection of C. perfringens in the feces, a disease caused by Clostridia is not diagnosable. In a study in Switzerland, 54 % of the C. perfringens isolates showed a reduced sensitivity towards metronidazole or 18 % towards tetracycline. Because there is a general risk of resistance formation, it is recommended to identify the triggering pathogen in principle.

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