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amino-terminal propeptide (PINP) antibody and antigen (Recombinant protein)
Diagnostic amino-terminal propeptide (PINP) antibodies (anti-amino-terminal propeptide, anti-PINP) and antigens (recombinant amino-terminal propeptide (PINP) protein) for Metabolic diseases PINP detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.
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Product information
| Catalog No. | Description | US $ Price (per mg) |
|---|---|---|
| GMP-h-PINP-Ag01 | Recombinant human COL1A1/PINP Protein | 3090 |
| GMP-h-PINP-Ab01 | Anti-human COL1A1/PINP mouse monoclonal antibody (mAb) | 1953 |
| GMP-h-PINP-Ab02 | Anti-human COL1A1/PINP mouse monoclonal antibody (mAb) | 1953 |
| GMP-h-PINP-Ab03 | Anti-human COL1A1/PINP human monoclonal antibody (mAb) | 1953 |
| GMP-h-PINP-Ab04 | Anti-human COL1A1/PINP human monoclonal antibody (mAb) | 1953 |
Size： 1mg | 10mg | 100mg
Product Description
| Cat No. of Products | GMP-h-PINP-Ag01 |
| Product Name | Recombinant human COL1A1/PINP Protein |
| Target/Biomarker | amino-terminal propeptide(PINP) |
| Alias of Target/Biomarker | CAFYD, EDSARTH1, EDSC, OI1, OI2, OI3, OI4 |
| Expression platform | mammalian |
| Isotypes | Recombinant Antigen |
| Bioactivity validation | amino-terminal propeptide (PINP) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PINP level test of Metabolic diseases (osteoporosis therapy) and related syndrome evaluation. |
| Products description | Recombinant human COL1A1/PINP Protein was expressed in mammalian expression system and is expressed with 6 HIS tag at the C-terminus. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | Standard substance, positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT. |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS,PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. of Products | GMP-h-PINP-Ab01, GMP-h-PINP-Ab02 |
| Product Name | Anti-human COL1A1/PINP mouse monoclonal antibody (mAb) |
| Target/Biomarker | amino-terminal propeptide(PINP) |
| Alias of Target/Biomarker | CAFYD, EDSARTH1, EDSC, OI1, OI2, OI3, OI4 |
| Expression platform | CHO |
| Isotypes | Mouse IgG |
| Bioactivity validation | Human amino-terminal propeptide (PINP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other amino-terminal propeptide (PINP) antibodies in PINP level test of Metabolic diseases (osteoporosis therapy) and related syndrome evaluation. |
| Tag | mFc |
| Products description | Anti-human COL1A1/PINP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS,PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
| Cat No. of Products | GMP-h-PINP-Ab03, GMP-h-PINP-Ab04 |
| Product Name | Anti-human COL1A1/PINP human monoclonal antibody (mAb) |
| Target/Biomarker | amino-terminal propeptide(PINP) |
| Alias of Target/Biomarker | CAFYD, EDSARTH1, EDSC, OI1, OI2, OI3, OI4 |
| Expression platform | CHO |
| Isotypes | Human lgG1 |
| Bioactivity validation | Human amino-terminal propeptide (PINP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other amino-terminal propeptide (PINP) antibodies in PINP level test of Metabolic diseases (osteoporosis therapy) and related syndrome evaluation. |
| Tag | hFc |
| Products description | Anti-human COL1A1/PINP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
| Purity | Purity: ≥95% (SDS-PAGE) |
| Application | ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT. |
| Formulation | Supplied as a 0.2 μM filtered solution of PBS,PH7.4. |
| Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
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Target/Biomarker information
Procollagen type I propeptides are derived from collagen type I, which is the most common collagen type found in mineralized bone. In bone, collagen is synthesized by osteoblasts in the form of procollagen. This precursor contains a short signal sequence and terminal extension peptides: amino-terminal propeptide (PINP) and carboxy-terminal propeptide. These propeptide extensions are removed by specific proteinases before the collagen molecules form. Both propeptides can be found in the circulation and their concentration reflects the synthesis rate of collagen type I. Although collagen type I propeptides may also arise from other tissues (such as the skin, vessels, fibrocartilage, and tendons), most nonskeletal tissues exhibit a slower turnover than bone, and contribute very little to the circulating pool of PINP. PINP is considered the most sensitive marker of bone formation and it is particularly useful for monitoring bone formation therapies and antiresorptive therapies; it is recommended that the test be performed at baseline before starting osteoporosis therapy and performed again 3 to 6 months later.
About GDU
GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.
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