amino-terminal propeptide (PINP) antibody and antigen (Recombinant protein)

Diagnostic amino-terminal propeptide (PINP) antibodies (anti-amino-terminal propeptide, anti-PINP) and antigens (recombinant amino-terminal propeptide (PINP) protein) for Metabolic diseases PINP detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.

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Product information

Catalog No. Description US $ Price (per mg)
GMP-h-PINP-Ag01 Recombinant human PINP Protein $3090.00
GMP-h-PINP-Ab01 Anti-human PINP mouse monoclonal antibody (mAb) $1953.00
GMP-h-PINP-Ab02 Anti-human PINP mouse monoclonal antibody (mAb) $1953.00
GMP-h-PINP-Ab03 Anti-human PINP human monoclonal antibody (mAb) $1953.00
GMP-h-PINP-Ab04 Anti-human PINP human monoclonal antibody (mAb) $1953.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. of Pruducts GMP-h-PINP-Ag01
Product Name Recombinant human PINP Protein
Target/Biomarker amino-terminal propeptide (PINP)
Alias of Target/Biomarker #N/A
Expression platform mammalian
Isotypes Recombinant Antigen
Bioactivity validation amino-terminal propeptide (PINP) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PINP level test of Metabolic diseases (osteoporosis therapy) and related syndrome evaluation
Products description Recombinant Human amino-terminal propeptide (PINP) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Pruducts GMP-h-PINP-Ab01,GMP-h-PINP-Ab02
Product Name Anti-human PINP mouse monoclonal antibody (mAb)
Target/Biomarker amino-terminal propeptide (PINP)
Alias of Target/Biomarker #N/A
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Human amino-terminal propeptide (PINP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other amino-terminal propeptide (PINP) antibodies in PINP level test of Metabolic diseases (osteoporosis therapy) and related syndrome evaluation.
Tag mFc
Products description Anti-human PINP mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other amino-terminal propeptide (PINP) antibodies.
Reconized/Reactive Species Human
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No. of Pruducts GMP-h-PINP-Ab03,GMP-h-PINP-Ab04
Product Name Anti-human PINP human monoclonal antibody (mAb)
Target/Biomarker amino-terminal propeptide (PINP)
Alias of Target/Biomarker #N/A
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Human amino-terminal propeptide (PINP) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other amino-terminal propeptide (PINP) antibodies in PINP level test of Metabolic diseases (osteoporosis therapy) and related syndrome evaluation.
Tag hFc
Products description Anti-human PINP mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Reconized/Reactive Species Human
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT.
Formulation Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker information

    Procollagen type I propeptides are derived from collagen type I, which is the most common collagen type found in mineralized bone. In bone, collagen is synthesized by osteoblasts in the form of procollagen. This precursor contains a short signal sequence and terminal extension peptides: amino-terminal propeptide (PINP) and carboxy-terminal propeptide. These propeptide extensions are removed by specific proteinases before the collagen molecules form. Both propeptides can be found in the circulation and their concentration reflects the synthesis rate of collagen type I. Although collagen type I propeptides may also arise from other tissues (such as the skin, vessels, fibrocartilage, and tendons), most nonskeletal tissues exhibit a slower turnover than bone, and contribute very little to the circulating pool of PINP. PINP is considered the most sensitive marker of bone formation and it is particularly useful for monitoring bone formation therapies and antiresorptive therapies; it is recommended that the test be performed at baseline before starting osteoporosis therapy and performed again 3 to 6 months later.



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    GDU

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