Protein induced by vitamin K absence-II (PIVKA-Ⅱ) antibody and antigen (Recombinant protein)
Diagnostic Protein induced by vitamin K absence-II (PIVKA-Ⅱ) antibodies (anti-Protein induced by vitamin K absence-II, anti-PIVKA-Ⅱ) and antigens (recombinant Protein induced by vitamin K absence-II (PIVKA-Ⅱ) protein) for Cancer PIVKA-Ⅱ detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.
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Product information
Catalog No. | Description | US $ Price (per mg) |
---|---|---|
GMP-h-PIVKA-Ⅱ-Ag01 | Recombinant human PIVKA-Ⅱ Protein | $3090.00 |
GMP-h-PIVKA-Ⅱ-Ab01 | Anti-human PIVKA-Ⅱ mouse monoclonal antibody (mAb) | $1953.00 |
GMP-h-PIVKA-Ⅱ-Ab02 | Anti-human PIVKA-Ⅱ mouse monoclonal antibody (mAb) | $1953.00 |
GMP-h-PIVKA-Ⅱ-Ab03 | Anti-human PIVKA-Ⅱ human monoclonal antibody (mAb) | $1953.00 |
GMP-h-PIVKA-Ⅱ-Ab04 | Anti-human PIVKA-Ⅱ human monoclonal antibody (mAb) | $1953.00 |
Size: 1mg | 10mg | 100mg
Product Description
Cat No. of Pruducts | GMP-h-PIVKA-Ⅱ-Ag01 |
Product Name | Recombinant human PIVKA-Ⅱ Protein |
Target/Biomarker | Protein induced by vitamin K absence-II (PIVKA-Ⅱ) |
Alias of Target/Biomarker | #N/A |
Expression platform | mammalian |
Isotypes | Recombinant Antigen |
Bioactivity validation | Protein induced by vitamin K absence-II (PIVKA-Ⅱ) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PIVKA-Ⅱ level test of Cancer (hepatocellular carcinoma) and related syndrome evaluation |
Products description | Recombinant Human Protein induced by vitamin K absence-II (PIVKA-Ⅱ) protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus. |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. of Pruducts | GMP-h-PIVKA-Ⅱ-Ab01,GMP-h-PIVKA-Ⅱ-Ab02 |
Product Name | Anti-human PIVKA-Ⅱ mouse monoclonal antibody (mAb) |
Target/Biomarker | Protein induced by vitamin K absence-II (PIVKA-Ⅱ) |
Alias of Target/Biomarker | #N/A |
Expression platform | CHO |
Isotypes | Mouse IgG |
Bioactivity validation | Human Protein induced by vitamin K absence-II (PIVKA-Ⅱ) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Protein induced by vitamin K absence-II (PIVKA-Ⅱ) antibodies in PIVKA-Ⅱ level test of Cancer (hepatocellular carcinoma) and related syndrome evaluation. |
Tag | mFc |
Products description | Anti-human PIVKA-Ⅱ mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other Protein induced by vitamin K absence-II (PIVKA-Ⅱ) antibodies. |
Reconized/Reactive Species | Human |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Cat No. of Pruducts | GMP-h-PIVKA-Ⅱ-Ab03,GMP-h-PIVKA-Ⅱ-Ab04 |
Product Name | Anti-human PIVKA-Ⅱ human monoclonal antibody (mAb) |
Target/Biomarker | Protein induced by vitamin K absence-II (PIVKA-Ⅱ) |
Alias of Target/Biomarker | #N/A |
Expression platform | CHO |
Isotypes | Human lgG1 |
Bioactivity validation | Human Protein induced by vitamin K absence-II (PIVKA-Ⅱ) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other Protein induced by vitamin K absence-II (PIVKA-Ⅱ) antibodies in PIVKA-Ⅱ level test of Cancer (hepatocellular carcinoma) and related syndrome evaluation. |
Tag | hFc |
Products description | Anti-human PIVKA-Ⅱ mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair. |
Reconized/Reactive Species | Human |
Purity | Purity: ≥95% (SDS-PAGE) |
Application | ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA),immunonephelometry and POCT. |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Target/Biomarker information
Protein induced by vitamin K absence-II (PIVKA-II) is a potential screening marker for hepatocellular carcinoma (HCC). Protein induced by vitamin K absence-II (PIVKA-II), also known as des-γ-carboxy-prothrombin, has been identified as a serum biomarker linked to HCC. It is an abnormal prothrombin molecule produced as a consequence of an acquired defect in the posttranslational carboxylation of the prothrombin precursor in malignant cells. A quite large body of evidence indicates that PIVKA-II levels in the blood are increased in patients with HCC and importantly, an increasing amount of data indicates that it is more sensitive than AFP for differentiating HCC at all stages from patients with cirrhosis or chronic hepatitis. In addition, several studies from Asian countries have shown that serum PIVKA-II levels correlate with the HCC stage, as well as with survival of HCC patients, and a combination of PIVKA-II and AFP is currently used in Japan for HCC diagnosis and surveillance in accordance with the recommendations of the Clinical Practice Guidelines for HCC of that country.
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