Recombinant multi-species PDE4B/ DPDE4/ PDEIVB protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDE4B protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: PDE4B, gene name: PDE4B, also named as DPDE4, PDEIVB. This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2014].

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Catalog No.	Product Name	Species	Size	Price
GM-Tg-hg-IP0041-Ag-1	Human PDE4B protein	Human	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-rg-IP0041-Ag-1	Rat PDE4B protein	Rat	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-mg-IP0041-Ag-1	Mouse PDE4B protein	Mouse	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cynog-IP0041-Ag-1	Cynomolgus/ Rhesus macaque PDE4B protein	Cynomolgus/ Rhesus macaque	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-felg-IP0041-Ag-1	Feline PDE4B protein	Feline	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-cang-IP0041-Ag-1	Canine PDE4B protein	Canine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-IP0041-Ag-1	Bovine PDE4B protein	Bovine	1mg/10mg/100mg/≥100mg	Inquiry
GM-Tg-bovg-IP0041-Ag-1	Equine PDE4B protein	Equine	1mg/10mg/100mg/≥100mg	Inquiry
Shipping Cost:				760.00

Description

Catalog No.	GM-Tg-hg-IP0041-Ag, GM-Tg-rg-IP0041-Ag, GM-Tg-mg-IP0041-Ag, GM-Tg-cynog-IP0041-Ag, GM-Tg-felg-IP0041-Ag, GM-Tg-cang-IP0041-Ag, GM-Tg-bovg-IP0041-Ag, GM-Tg-equg-IP0041-Ag-1
Products Name	PDE4B protein
Species	Human, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target Name	PDE4B
Protein Sub-location	Introcelluar Protein
Isotypes	Recombinant protein
Expression platform	Mammalian cell
Bioactivity validation	Affintiy&bioactivity validated by ELISA, cell culture validated.
Tag	His
Products description	Recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine PDE4B protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
Purity	Purity: ≥95% (SDS-PAGE)
Application	In vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation	Supplied as a 0.2 μM filtered solution of PBS, PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.