Recombinant multi-species NSMA3/ SMPD4/ NET13 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to SMPD4/SMPD4 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SMPD4 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: SMPD4, gene name: SMPD4, also named as NET13, NSMASE-3, NSMASE3, SKNY. The protein encoded by this gene is a sphingomyelinase that catalyzes the hydrolysis of membrane sphingomyelin to form phosphorylcholine and ceramide. This gene is activated by DNA damage, cellular stress, and tumor necrosis factor, but it is downregulated by wild-type p53. The encoded protein localizes to the endoplasmic reticulum and Golgi network. [provided by RefSeq, Mar 2017].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0101-Ag-1Human SMPD4 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0101-Ag-1Rat SMPD4 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0101-Ag-1Mouse SMPD4 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0101-Ag-1Cynomolgus/ Rhesus macaque SMPD4 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0101-Ag-1Feline SMPD4 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0101-Ag-1Canine SMPD4 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0101-Ag-1Bovine SMPD4 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0101-Ag-1Equine SMPD4 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-IP0101-Ag, GM-Tg-rg-IP0101-Ag, GM-Tg-mg-IP0101-Ag, GM-Tg-cynog-IP0101-Ag,
GM-Tg-felg-IP0101-Ag, GM-Tg-cang-IP0101-Ag, GM-Tg-bovg-IP0101-Ag, GM-Tg-equg-IP0101-Ag-1
Products Name SMPD4 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameSMPD4
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SMPD4 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.