Recombinant multi-species ALG11/ CDG1P/ GT8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to ALG11/ALG11 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALG11 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: ALG11, gene name: ALG11, also named as CDG1P, GT8. This gene encodes a GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase which is localized to the cytosolic side of the endoplasmic reticulum (ER) and catalyzes the transfer of the fourth and fifth mannose residue from GDP-mannose (GDP-Man) to Man3GlcNAc2-PP-dolichol and Man4GlcNAc2-PP-dolichol resulting in the production of Man5GlcNAc2-PP-dolichol. Mutations in this gene are associated with congenital disorder of glycosylation type Ip (CDGIP). This gene overlaps but is distinct from the UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast) gene. A pseudogene of the GDP-Man:Man3GlcNAc2-PP-dolichol-alpha1,2-mannosyltransferase has been identified on chromosome 19. [provided by RefSeq, Aug 2010].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0317-Ag-1Human ALG11 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0317-Ag-1Rat ALG11 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0317-Ag-1Mouse ALG11 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0317-Ag-1Cynomolgus/ Rhesus macaque ALG11 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0317-Ag-1Feline ALG11 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0317-Ag-1Canine ALG11 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0317-Ag-1Bovine ALG11 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0317-Ag-1Equine ALG11 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP0317-Ag, GM-Tg-rg-IP0317-Ag, GM-Tg-mg-IP0317-Ag, GM-Tg-cynog-IP0317-Ag,
GM-Tg-felg-IP0317-Ag, GM-Tg-cang-IP0317-Ag, GM-Tg-bovg-IP0317-Ag, GM-Tg-equg-IP0317-Ag-1
Products Name ALG11 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameALG11
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine ALG11 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.