Recombinant multi-species EI24/ EPG4/ PIG8 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to EI24/EI24 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EI24 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: EI24, gene name: EI24, also named as EPG4, PIG8, TP53I8. This gene encodes a putative tumor suppressor and has higher expression in p53-expressing cells than in control cells and is an immediate-early induction target of p53-mediated apoptosis. The encoded protein may suppress cell growth by inducing apoptotic cell death through the caspase 9 and mitochondrial pathways. This gene is located on human chromosome 11q24, a region frequently altered in cancers. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 1, 3, 7, and 8. [provided by RefSeq, Feb 2014].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP0742-Ag-1Human EI24 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP0742-Ag-1Rat EI24 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP0742-Ag-1Mouse EI24 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP0742-Ag-1Cynomolgus/ Rhesus macaque EI24 proteinCynomolgus/
Rhesus macaque
1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP0742-Ag-1Feline EI24 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP0742-Ag-1Canine EI24 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0742-Ag-1Bovine EI24 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP0742-Ag-1Equine EI24 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00



Description

Catalog No.GM-Tg-hg-IP0742-Ag, GM-Tg-rg-IP0742-Ag, GM-Tg-mg-IP0742-Ag, GM-Tg-cynog-IP0742-Ag,
GM-Tg-felg-IP0742-Ag, GM-Tg-cang-IP0742-Ag, GM-Tg-bovg-IP0742-Ag, GM-Tg-equg-IP0742-Ag-1
Products Name EI24 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameEI24
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine EI24 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.