Recombinant multi-species SACA1/ SPACA1/ SAMP32 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Target products collectionGo to SPACA1/SPACA1 products collection >>
(antibodies, antigen, VLP, mRNA, ORF viral vector, etc)

Genemedi produces recombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SPACA1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

The target: SPACA1, gene name: SPACA1, also named as SAMP32. The correlation of anti-sperm antibodies with cases of unexplained infertility implicates a role for these antibodies in blocking fertilization. Improved diagnosis and treatment of immunologic infertility, as well as identification of proteins for targeted contraception, are dependent on the identification and characterization of relevant sperm antigens. The protein expressed by this gene is recognized by anti-sperm antibodies from infertile males. Furthermore, antibodies generated against the recombinant protein block in vitro fertilization. This protein localizes to the acrosomal membrane of spermatids and mature spermatozoa where it is thought to play a role in acrosomal morphogenesis and in sperm-egg binding and fusion, respectively. [provided by RefSeq, Jul 2008].

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Catalog No.Product NameSpeciesSizePrice
GM-Tg-hg-IP1790-Ag-1Human SPACA1 proteinHuman1mg/10mg/100mg/≥100mgInquiry
GM-Tg-rg-IP1790-Ag-1Rat SPACA1 proteinRat1mg/10mg/100mg/≥100mgInquiry
GM-Tg-mg-IP1790-Ag-1Mouse SPACA1 proteinMouse1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cynog-IP1790-Ag-1Cynomolgus/ Rhesus macaque SPACA1 proteinCynomolgus/
Rhesus macaque		1mg/10mg/100mg/≥100mgInquiry
GM-Tg-felg-IP1790-Ag-1Feline SPACA1 proteinFeline1mg/10mg/100mg/≥100mgInquiry
GM-Tg-cang-IP1790-Ag-1Canine SPACA1 proteinCanine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP1790-Ag-1Bovine SPACA1 proteinBovine1mg/10mg/100mg/≥100mgInquiry
GM-Tg-bovg-IP1790-Ag-1Equine SPACA1 proteinEquine1mg/10mg/100mg/≥100mgInquiry
Shipping Cost:760.00

For more than 100mg, click here forinquiry.>>


Description

Catalog No.GM-Tg-hg-IP1790-Ag, GM-Tg-rg-IP1790-Ag, GM-Tg-mg-IP1790-Ag, GM-Tg-cynog-IP1790-Ag,
GM-Tg-felg-IP1790-Ag, GM-Tg-cang-IP1790-Ag, GM-Tg-bovg-IP1790-Ag, GM-Tg-equg-IP1790-Ag-1
Products Name SPACA1 protein
SpeciesHuman, Cynomolgus/ Rhesus macaque, rat, mouse, Feline, Canine, Bovine, Equine
Target NameSPACA1
Protein Sub-locationIntrocelluar Protein
IsotypesRecombinant protein
Expression platform Mammalian cell
Bioactivity validationAffintiy&bioactivity validated by ELISA, cell culture validated.
TagHis
Products descriptionRecombinant Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine SPACA1 protein was expressed in mammalian cell expression system and is expressed with 6 HIS tag at the C-terminus for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic).
PurityPurity: ≥95% (SDS-PAGE)
ApplicationIn vitro study, in vivo study, benchmark, positive control for the diagnosis. Biological drug disovery including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Formulation & ReconstitutionLyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4);
For PSB2, reconstituted with 0.9% sodium chloride;
For PBS, reconstituted with ddH2O.
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.